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24 <strong>Lundbeck</strong> Magazine 2009<br />

"Unfortunately, there are<br />

still major differences in the<br />

treatment on offer to patients in<br />

different countries in Europe"<br />

Everyone agrees that patients with a<br />

myocardial infarct should be treated by<br />

cardiologists, but the attitude was that anyone<br />

could treat stroke patients,” Markku Kaste says.<br />

When he was able to document on the basis<br />

of a study that stroke patients who had been<br />

treated by neurologists were able to leave<br />

hospital 16 days earlier than those treated in<br />

other wards, and that more were discharged to<br />

their own homes and were also better able to<br />

care for themselves without help, the Helsinki<br />

City Council saw the light. That happened in<br />

1995. The stroke unit at HUCH Meilahti<br />

hospital has since treated all acute stroke<br />

patients in Helsinki. The experience gained in<br />

acute care of stroke has been formulated as<br />

European guidelines. The recommendations,<br />

previously written by a task force of the<br />

European Stroke Initiative (EUSI) and later on<br />

by the European Stroke Organisation (ESO),<br />

both of which Markku Kaste helped found, are<br />

available in multiple languages.<br />

Four out of ten neglected<br />

“Unfortunately, there are still major differences<br />

in the treatment on offer to patients in<br />

different countries in Europe. Recently we<br />

asked 4261 randomly selected hospitals<br />

throughout the EU about their treatment of<br />

stroke, and the results were shocking. Only one<br />

out of seven patients – between 13 and 14 per<br />

cent – were treated as recommended by WHO<br />

i.e. in a stroke unit at a university hospital or<br />

other well equipped hospital, which has<br />

neurologists, cardiologists, neurosurgeons,<br />

vascular surgeons, and a CT scanner that is<br />

manned 24 hours a day. Forty-four per cent<br />

receive acceptable treatment, generally at<br />

large hospital centres. But the remaining 42<br />

per cent are treated in hospitals that lack both<br />

equipment and experience. And this happens<br />

in rich countries as well as in poor. This is not<br />

only appalling for patients, it is also costly for<br />

society,” Markku Kaste says.<br />

Too weak to bang on the table<br />

Stroke is an illness which costs society a lot<br />

of money. “In Finland, caring for a patient in<br />

a nursing home costs EUR 50,000 per year.<br />

As strokes generally occur in persons between<br />

the ages of 60 and 70, their life expectancy is<br />

higher than, for example, persons with<br />

dementia, who are usually older when they<br />

enter a nursing home. Stroke is exceedingly<br />

expensive for society, but those who have<br />

suffered a stroke are too weak to bang on<br />

the table and demand better treatment. This<br />

makes it important to prevent the illness –<br />

also from an economic point of view,”<br />

Professor Kaste continues.<br />

The factors that can cause stroke are the same<br />

as those that can cause cardiovascular<br />

diseases: high blood pressure, high cholesterol,<br />

obesity, smoking, high alcohol consumption<br />

and lack of physical exercise.<br />

Quick treatment makes the difference<br />

“It is therefore possible to do something<br />

oneself, and prevention is of course the best<br />

mode of action. But for those who suffer a<br />

stroke anyway, it is important for society to<br />

invest in stroke units where it is possible to<br />

obtain the best possible treatment, which<br />

increases the likelihood of good recovery. With<br />

the present drugs for dissolving blood clots, we<br />

consider it possible to save many patients up<br />

until four and a half hours of the time of the<br />

symptom onset and in some patients even<br />

after longer time before irreversible damage<br />

occurs. We are currently investigating a new<br />

drug which may give us as much as nine hours,<br />

and thus more time to get patients to<br />

hospitals that can provide the right treatment.<br />

Some patients cannot tolerate drugs that solve<br />

the blood clot, which occludes the brain artery,<br />

for example if they have very high blood<br />

pressure or internal bleeding. But quick arrival<br />

at the hospital and appropriate treatment<br />

benefit all patients. Competent intervention by<br />

a wide spectrum of specialists reduces the risk<br />

of the patient dying or becoming helpless and<br />

requiring care. Quick and correct treatment is<br />

good for the individual patient, and a major<br />

economic benefit for society,” says Professor<br />

Markku Kaste.<br />

PHOTO: Joachim ladefoged

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