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<strong>Lundbeck</strong> Magazine 2009<br />

41<br />

s an active researcher, Anne-Marie<br />

Engel was so successful at applying<br />

for and obtaining financing for her<br />

research that she taught her colleagues how<br />

to write applications that get the desired<br />

results. Now, she is on the other side of the<br />

table. As Director of Research at the <strong>Lundbeck</strong><br />

Foundation and secretary of its selection<br />

committee, Anne-Marie Engel is involved in<br />

processing the approximately 600 applications<br />

for funds for research purposes in the health<br />

and natural sciences which the Foundation<br />

receives annually.<br />

The selection committee has eight members,<br />

three of whom are on the board of the<br />

<strong>Lundbeck</strong> Foundation, and three of whom are<br />

scientific experts in Denmark’s neighbouring<br />

countries. The eight members gather three<br />

times a year to assess the individual<br />

applications, in order to provide the best<br />

possible basis for the Board of the <strong>Lundbeck</strong><br />

Foundation to distribute the large amounts<br />

of money at its disposal. Between 2008 and<br />

2010, the Foundation will distribute<br />

approximately DKK 1 billion.<br />

Many excellent researchers<br />

The first requirement is that research must be<br />

top quality, a criterion that applicants normally<br />

have no difficulty in meeting.<br />

“We see many good applications, and it is<br />

my impression that we have many excellent<br />

researchers in Denmark. Research projects<br />

must be in either the health or natural<br />

sciences. The foundation has a long tradition<br />

of supporting neurological research, though we<br />

also give money to many other fields within<br />

the health sciences. In recent years, we have<br />

given money for research in areas such as cell<br />

biology and cell communication. We have also<br />

donated to translation, which deals with<br />

building bridges between basic and clinical<br />

research that is done with a view to<br />

discovering improved methods of treatment<br />

based, among other things, on new knowledge<br />

of the role of genes in development of certain<br />

diseases. If scientists can map the significance<br />

of genes in development of illnesses such as<br />

asthma and various life-style diseases, it will<br />

have major consequences for both treatment<br />

and prevention,” Anne-Marie Engel says.<br />

Focus on intervention<br />

Intervention is another area of current interest<br />

to researchers.<br />

“In 2008 we supported the establishment of<br />

three centres. At the first centre, research is<br />

being done to optimize radiation treatment<br />

of various types of cancer, and at the second<br />

centre efforts are being made to discover a more<br />

efficient and less traumatic method of replacing<br />

knees and hips. The third centre focuses on<br />

neurological research, namely schizophrenia.<br />

Danish scientists have helped establish the<br />

existence of a chromosomal error that causes<br />

susceptibility to schizophrenia – a discovery that<br />

may well change the perception of persons with<br />

psychiatric disorders – the same as discovery of<br />

the bacteria that causes stomach ulcer has done<br />

for persons with that disorder. These persons<br />

used to be considered ‘delicate’. We now know<br />

that the illness has a physiological cause,” Anne-<br />

Marie Engel continues.<br />

A few years ago, the Board of the <strong>Lundbeck</strong><br />

Foundation also decided to earmark an amount<br />

for research in physics and chemistry, and the<br />

Foundation has also given money to projects<br />

such as Danish scientists’ studies of the universe.<br />

“It is very difficult to obtain financing for this<br />

type of research in Denmark, while there are<br />

many foundations that support research in the<br />

health sciences. The <strong>Lundbeck</strong> Foundation<br />

wishes to support Danish research on a broad<br />

front. We believe it is important to have a<br />

dynamic research environment in Denmark,”<br />

states Anne-Marie Engel.<br />

Too few young people<br />

She is a medical doctor, and became<br />

fascinated by research. She was employed as<br />

a researcher at Statens Serum Institute when<br />

she saw a job advert from the <strong>Lundbeck</strong><br />

Foundation. Much of the work consisted of<br />

reading applications and writing an<br />

introduction to them.<br />

“It was the ideal job for me. I was always<br />

reasonably lucky with writing applications to<br />

foundations to finance my research. Later, I<br />

taught others how to write successful<br />

applications to foundations that had<br />

previously turned them down,” Anne-Marie<br />

Engel continues.<br />

Her greatest concern for research is the fact<br />

that too few young people are studying for<br />

degrees in the natural sciences.<br />

“It would be unfortunate if the falling<br />

tendency continues. For this reason, the<br />

<strong>Lundbeck</strong> Foundation is supporting a number<br />

of initiatives that seek to influence students’<br />

choice of field of study during their early years<br />

at school. This must be done at a stage when<br />

they are still asking spontaneous questions<br />

about nature, and, among other things, the<br />

initiatives involve strengthening instruction in<br />

nature and technology for the youngest<br />

children in primary schools. Teachers must<br />

have more possibilities for making<br />

experiments. Children love classes where they<br />

are able to experiment, and they remember<br />

them for a long time – perhaps for the rest of<br />

their lives. Stimulating young people’s pleasure<br />

in the natural sciences is very close to my<br />

heart,” concludes Anne-Marie Engel.<br />

The <strong>Lundbeck</strong> Foundation is a commercial foundation which was established in 1954 by Mrs Grete<br />

<strong>Lundbeck</strong>, the widow of the founder of H. <strong>Lundbeck</strong> A/S. The primary aim of the Foundation is to<br />

maintain and expand the activities of the <strong>Lundbeck</strong> Group, and to provide funding for research of the<br />

highest quality in the health and natural sciences.<br />

In 2007 and 2008, the Foundation supported the establishment of research centres whose aim is<br />

to make the results of basic scientific research available for patients as quickly and efficiently as<br />

possible. The theme for 2009 is nanomedicine.<br />

In 2008, the <strong>Lundbeck</strong> Foundation donated DKK 328 million to research.<br />

PHOTO: Joachim ladefoged

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