Chapter 7 The Control of Microbial Growth
Chapter 7 The Control of Microbial Growth
Chapter 7 The Control of Microbial Growth
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Aldehydes and Chemical Sterilants<br />
Aldehydes (alkylating agents)<br />
• Inactivate proteins by cross-linking<br />
with functional groups<br />
(–NH 2 , –OH, –COOH, –SH)<br />
• Glutaraldehyde: Sterilant for<br />
delicate surgical instruments<br />
(Kills S. aureus in 5,<br />
M. tuberculosis in 10 min)<br />
• Formaldehyde: Virus inactivation<br />
for vaccines<br />
Chemical Sterilants for heat sensive material<br />
• Denature proteins<br />
• Ethylene oxide<br />
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