History of Clinical Research - IPPCR Video and Handout Archive
History of Clinical Research - IPPCR Video and Handout Archive
History of Clinical Research - IPPCR Video and Handout Archive
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James Lind<br />
<strong>History</strong> <strong>of</strong> <strong>Clinical</strong> Trials<br />
• Scurvy was a major health problem for the British<br />
Navy in the 1700’s.<br />
• William Harvey had recommended lemons to treat<br />
scurvy, but had argued that the<br />
therapeutic effect was a result <strong>of</strong> the acid<br />
in the fruit.<br />
• James Lind, a naval surgeon, conducted a<br />
clinical trial in 1747 to assess the utility <strong>of</strong><br />
three therapies for scurvy.<br />
(1716 – 1794)<br />
Born in Edinburgh, Scotl<strong>and</strong>
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