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History of Clinical Research - IPPCR Video and Handout Archive

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Girl with smallpox<br />

(1) Al-Rhazi– 1 st description <strong>of</strong><br />

smallpox ~900 AD A.D.<br />

(2) In the 11th century, protective<br />

measures for smallpox included:<br />

d<br />

• Putting scabs from smallpox<br />

pustules in the nostrils<br />

• Wearing the clothing <strong>of</strong> someone<br />

who had the disease<br />

Chinese artist rendition <strong>of</strong> a girl<br />

with smallpox<br />

• Ingesting powdered fleas from<br />

infected cows (may have<br />

perceived relationship <strong>of</strong> cowpox<br />

to smallpox)

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