Weak Interactions and Hydrogen Bonding

Latimer and Rodebush in 1920 introduced the term
“Hydrogen bond” to describe the nature of
association in the liquid state of water, hydrogen
fluoride, & so on.
(1) D:H:A (responsible for m.p. & b.p.)
(2) D-H (O, F, N) … A
~ 4 - 50 kJ/mol for neutral molecules
(~ 100 - 400 kJ/mol for typical covalent bonds)