open access: Nature Reviews: Key Advances in Medicine

Cover image: Hippocrates of Cos
reflected in the style of the Roman
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by Peter Paul Rubens (1638) from
ihm.nlm.nih.gov website.
design: annette fenner & nicola hawes
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Key Advances in Medicine
The articles included in Nature Reviews Key Advances in
Medicine were originally published in the February 2012
issues of the eight clinical Nature Reviews journals. The journals’
editors commissioned international experts to write a short
essay highlighting up to five key papers that made the biggest
contribution to their field in 2011. Between them, the eight clinical
Nature Reviews journals published 43 articles, which are collated
in this eBook; if you choose to cite an article, please use the
original journal citation rather than citing the eBook.
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Nature Reviews Cardiology
S1 acute coronary syndromes | Walking the tightrope between efficacy and bleeding
Payal Kohli and Christopher P. Cannon
S3 atrial fibrillation | Stroke prevention in AF
Gregory Y. H. Lip
S5 heart failure | Heart failure therapy—technology to the fore
John J. V. McMurray
S7 hypertension | New insights—from risk factors to treatment implications
George L. Bakris
S9 valvular disease | Breakthrough for intervention?
Volkmar Falk
Nature Reviews Clinical Oncology
S11 ovarian cancer | Mutations and non-inferiority analyses show a way forward
Maurie Markman
S12 prostate cancer | Hitting old targets better and identifying new targets
Yu Chen and Howard I. Scher
S14 hematological cancer | New therapeutic targets and treatment strategies
Paula Cramer and Michael Hallek
S16 melanoma | A new paradigm tumor for drug development
Alexander M. M. Eggermont and Caroline Robert
S18 bone cancer | Prevention and treatment of bone metastases
Robert E. Coleman