2007 Annual Report - Foundation for the National Institutes of Health
2007 Annual Report - Foundation for the National Institutes of Health
2007 Annual Report - Foundation for the National Institutes of Health
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Osteorarthritis Initiative<br />
In <strong>2007</strong>, <strong>the</strong> Osteoarthritis Initiative (OAI) began to<br />
generate findings in journals and presentations, while it<br />
continued to release new data and images from its fiveyear<br />
study on knee health.<br />
The study, which tracks nearly 5,000 subjects over time,<br />
aims to increase understanding, and ultimately improve<br />
treatment <strong>of</strong> a major cause <strong>of</strong> disability among Americans.<br />
The most common type <strong>of</strong> arthritis, osteoarthritis affects<br />
more than 15 million people in <strong>the</strong> United States. By<br />
2030, 70 million Americans will be 65 years old or older<br />
and at risk <strong>for</strong> this progressive disease.<br />
So far, <strong>the</strong> initiative has released baseline clinical<br />
data on all participants, as well as 12- and 18-month<br />
follow-up data and images on many. When <strong>the</strong> study<br />
is complete, <strong>the</strong> in<strong>for</strong>mation will document <strong>the</strong> natural<br />
progression <strong>of</strong> <strong>the</strong> disease and help identify biomarkers<br />
associated with it, ideally hastening research and <strong>the</strong>rapies.<br />
The <strong>Foundation</strong> <strong>for</strong> NIH facilitated <strong>for</strong>mation <strong>of</strong> <strong>the</strong><br />
initiative, bringing toge<strong>the</strong>r seven components <strong>of</strong> NIH<br />
and four private-funding partners who have toge<strong>the</strong>r<br />
contributed more than $18.5 million.<br />
All OAI data and images are available to researchers<br />
worldwide, through <strong>the</strong> initiative’s web site at<br />
www.oai.ucsf.edu, along with tools to interpret <strong>the</strong>m.<br />
So far, almost 750 researchers from 40 different countries<br />
have registered with <strong>the</strong> site. Research abstracts<br />
and findings based on <strong>the</strong> data have appeared in several<br />
publications and in presentations be<strong>for</strong>e <strong>the</strong> American<br />
College <strong>of</strong> Rheumatology and <strong>the</strong> Osteoarthritis Research<br />
Society International.<br />
CONTRIBUTORS INCLUDE<br />
GlaxoSmithKline<br />
Merck & Co., Inc.<br />
Novartis<br />
Pfizer Inc<br />
“The <strong>Foundation</strong> <strong>for</strong> NIH has been<br />
and continues to be, critically<br />
important to <strong>the</strong> success <strong>of</strong> <strong>the</strong><br />
Osteoarthritis Initiative that is<br />
sponsored by many NIH institutes<br />
and <strong>of</strong>fices as well as industry.”<br />
—Stephen I. Katz, M.D.<br />
Director, <strong>National</strong> Institute <strong>of</strong><br />
Arthritis and Musculoskeletal<br />
and Skin Diseases at NIH<br />
<strong>Foundation</strong> <strong>for</strong> <strong>the</strong> <strong>National</strong> <strong>Institutes</strong> <strong>of</strong> <strong>Health</strong> www.fnih.org | 7
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