Program Perspectives in Cell- and Gene-Based Medicines - DGTI

P3
Clonality in Normal and Aberrant Regeneration
P3.01 Haematopoietic reconstitution kinetics after transplantation of
gene-marked stem cells on a clonal level
Kerstin Cornils, Hamburg
P3.02 A Novel Method of Combined Preconditioning and In Vivo Chemoselection
Using 6 Thioguanine Alone Results in Highly Efficient Reconstitution
of Normal Hematopoiesis with HPRT-deficient Bone Marrow
Katrin Hacke, Los Angeles
P3.03 Evi1 Activation Leads To Increased Genomic Instability In Hematopoietic
Cells
Andrea Kinner, Frankfurt
P3.04 Effect Of Deacetylase Inhibitor Treatment On Proliferation And
Self-Renewal Properties Of Leukemic Stem And Progenitor Cells
Annette Romanski, Frankfurt
P3.05 Low genotoxicity and flexible pseudotyping of alpharetroviral SIN
vectors
Verena Thies, Hannover
P3.06 High throughput integration site analysis of an X-CGD patient treated
with a lentiviral vector
Simone Scholz, Heidelberg
P3.07 Promoting Hematopoietic Engraftment By Conditioning With Cells
Overexpressing A Signaling-defective Thrombopoietin Receptor
(Mpl)
Sabine Wintterle, Hannover
P3.08 Humanized models to assess the genotoxicity of viral vectors in the
context of hematopoietic gene therapy and in vivo selection
Ruhi Phaltane, Hannover
P3.09 Use of the in vitro immortalization assay to quantify the impact of
vector design and integration pattern on insertional mutagenesis
Michael Rothe, Hannover
P3.10 Mature T-cell lymphoma induced by insertional transactivation of
the Janus kinase 1 gene after gammaretroviral transduction of
mature T lymphocytes
Tim Heinrich, Frankfurt
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