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ENGINEERING - Cambridge University Press India

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Essential<br />

Bioinformatics<br />

Jin Xiong<br />

Texas A & M <strong>University</strong><br />

Contents: Preface; 1. Introduction; 2. Cellular<br />

biomechanics; 3. Hemodynamics; 4. The<br />

circulatory system; 5. The interstitium; 6. Ocular<br />

biomechanics; 7. The respiratory system;<br />

8. Muscles and movement; 9. Skeletal<br />

biomechanics; 10. Terrestrial locomotion;<br />

Appendix A. The electrocardiogram; Index.<br />

ISBN: 9780521165181 528pp ` 1050.00<br />

Essential Bioinformatics is a concise yet<br />

comprehensive textbook of bioinformatics that<br />

provides a broad introduction to the entire field.<br />

Written specifically for a life science audience, the<br />

basics of bioinformatics are explained; followed by<br />

discussions of the state-of-the-art computational<br />

tools available to solve biological research<br />

problems. All key areas of bioinformatics are<br />

covered including biological databases, sequence<br />

alignment, genes and promoter prediction,<br />

molecular phylogenetics, structural bioinformatics,<br />

genomics, and proteomics. The book emphasizes<br />

how computational methods work and compares<br />

the strengths and weaknesses of different<br />

methods. This balanced yet easily accessible text<br />

will be invaluable to students who do not have<br />

sophisticated computational backgrounds.<br />

Technical details of computational algorithms are<br />

explained with a minimum use of mathematical<br />

formulas; graphical illustrations are used in their<br />

place to aid understanding. The effective synthesis<br />

of existing literature as well as in-depth and up-todate<br />

coverage of all key topics in bioinformatics<br />

make this an ideal textbook for all bioinformatics<br />

courses taken by life science students and for<br />

researchers wishing to develop their knowledge of<br />

bioinformatics to facilitate their own research.<br />

Contents: Preface; Part I. Introduction and<br />

Biological Databases: 1. Introduction;<br />

2. Introduction to biological databases; Part II.<br />

Sequence Alignment: 3. Pairwise sequence<br />

alignment; 4. Database similarity search;<br />

5. Multiple sequence alignment; 6. Profiles and<br />

hidden Markov models; 7. Protein motifs and<br />

patterns; Part III. Gene and Promoter Prediction:<br />

8. Gene prediction; 9. Promoter and regulatory<br />

element prediction; Part IV. Molecular<br />

Phylogenetics: 10. Phylogenetics basics;<br />

11. Phylogenetic tree construction methods and<br />

programs; Part V. Protein Structure Basics:<br />

12. Protein structure basics; 13. Protein structure<br />

visualization, comparison and classification;<br />

14. Protein secondary structure prediction;<br />

15. Protein tertiary structure prediction; 16. RNA<br />

structure prediction; Part VI. Genomics and<br />

Proteomics: 17. Genome mapping, assembly and<br />

comparison; 18. Functional genomics;<br />

19. Proteomics; Practical exercises; Glossary.<br />

ISBN: 9780521706100 339pp ` 445.00<br />

Biomedical<br />

Engineering<br />

Bridging Medicine and<br />

Technology<br />

W. Mark Saltzman<br />

Yale <strong>University</strong>,<br />

Connecticut<br />

Commercialising<br />

Successful<br />

Biomedical<br />

Technologies<br />

Basic Principles for the<br />

Development of Drugs,<br />

Diagnostics and Devices<br />

Shreefal S. Mehta,<br />

Cytopia<br />

This is an ideal text for an introduction to<br />

biomedical engineering. The book presents the<br />

basic science knowledge used by biomedical<br />

engineers at a level accessible to all students and<br />

illustrates the first steps in applying this knowledge<br />

to solve problems in human medicine. Biomedical<br />

engineering encompasses a range of fields of<br />

specialization including bioinstrumentation,<br />

bioimaging, biomechanics, biomaterials, and<br />

biomolecular engineering. This introduction to<br />

bioengineering assembles foundational resources<br />

from molecular and cellular biology and physiology<br />

and relates them to various sub-specialties of<br />

biomedical engineering. The first two parts of the<br />

book present basic information in molecular/<br />

cellular biology and human physiology;<br />

quantitative concepts are stressed in these<br />

sections. Comprehension of these basic life<br />

science principles provides the context in which<br />

biomedical engineers interact. The third part of the<br />

book introduces sub-specialties in biomedical<br />

engineering, and emphasizes - through examples<br />

and profiles of people in the field - the types of<br />

problems biomedical engineers solve.<br />

Contents: 1. Introduction; Part I. Molecular and<br />

Cellular Principles: 2. Biomolecular principles;<br />

3. Biomolecular principles: nucleic acids;<br />

4. Biomolecular principles: proteins; 5. Cellular<br />

principles; Part II. Physiological Principles:<br />

6. Communication systems in the body;<br />

7. Engineering balances: respiration and<br />

digestion; 8. Circulation; 9. Removal of molecules<br />

from the body; 10. Biomechanics;<br />

11. Bioinstrumentation; 12. Bioimaging;<br />

13. Biomolecular engineering and biotechnology;<br />

14. Biomolecular engineering II: engineering of<br />

immunity; 15. Biomaterials and artificial organs;<br />

16. Biomedical engineering and cancer.<br />

ISBN: 9780521840996 656pp $ 105.00<br />

Successful product design and development<br />

requires the ability to take a concept and translate<br />

the technology into useful, patentable, commercial<br />

products. This book guides the reader through the<br />

practical aspects of the commercialization process<br />

of drug, diagnostic and device biomedical<br />

technology including market analysis, product<br />

development, intellectual property and regulatory<br />

constraints. Key issues are highlighted at each<br />

stage in the process, and case studies are used to<br />

provide practical examples. The book will provide<br />

a sound road map for those involved in the<br />

biotechnology industry to effectively plan the<br />

commercialization of profitable regulated medical<br />

products. It will also be suitable for a capstone<br />

design course in engineering and biotechnology,<br />

providing the student with the business acumen<br />

skills involved in product development.<br />

Contents: Foreword; Glossary; 1. Biomedical<br />

device and drug design industry and markets;<br />

2. Markets of interest and market research steps;<br />

3. Intellectual property and licensing; 4. Product<br />

60

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