Targeting by probe-based circularisation
Targeting by probe-based circularisation
Targeting by probe-based circularisation
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Parallel sequencing of 177 exons in<br />
10 cancer genes<br />
454 sequencing<br />
59.000 reads per exp<br />
55%<br />
90% map to the selected<br />
sequence (49 kb) =><br />
Average enrichment:<br />
600.000<br />
10x<br />
508 <strong>probe</strong>s<br />
Dahl, et al. (2007) PNAS, 104, 9387-9392
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