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Targeting by probe-based circularisation

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Further development eop e<br />

• New <strong>probe</strong> design<br />

– reduced cost (4 EUR/<strong>probe</strong>)<br />

– More even representation ti (5-fold range)<br />

– Compatible with Solexa and SOLiD seq.<br />

• Double the size of selected fragments<br />

• Less input DNA (100 ng)<br />

• Applied to a cancer resequencing project<br />

with Tobias Sjöblom at UU.<br />

• Spun out a company:

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