Targeting by probe-based circularisation
Targeting by probe-based circularisation
Targeting by probe-based circularisation
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Further development eop e<br />
• New <strong>probe</strong> design<br />
– reduced cost (4 EUR/<strong>probe</strong>)<br />
– More even representation ti (5-fold range)<br />
– Compatible with Solexa and SOLiD seq.<br />
• Double the size of selected fragments<br />
• Less input DNA (100 ng)<br />
• Applied to a cancer resequencing project<br />
with Tobias Sjöblom at UU.<br />
• Spun out a company: