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Substance Misuse in Pregnancy - NHS Lothian

Substance Misuse in Pregnancy - NHS Lothian

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Effects of tobacco<br />

The significant risks associated with maternal use of tobacco are<br />

particularly well established. There are many harmful substances<br />

conta<strong>in</strong>ed <strong>in</strong> cigarettes. Nicot<strong>in</strong>e, carbon monoxide and cyanide are<br />

thought to have the greatest adverse effects, reduc<strong>in</strong>g blood flow and<br />

oxygen to the fetus.<br />

Maternal smok<strong>in</strong>g <strong>in</strong> the first 12 weeks of pregnancy (until the end of the<br />

1 st trimester) is responsible for up to 25% of all low birth weight babies<br />

(Scottish Executive 2001). Smok<strong>in</strong>g tobacco causes a reduction <strong>in</strong> birth<br />

weight greater than that from hero<strong>in</strong> and is a major risk factor <strong>in</strong> Sudden<br />

Infant Death Syndrome (Scottish Executive 2003).<br />

Although there is no conv<strong>in</strong>c<strong>in</strong>g evidence that smok<strong>in</strong>g cigarettes causes<br />

congenital birth defects, many other pregnancy complications are<br />

associated with smok<strong>in</strong>g (Johnstone 1998). These <strong>in</strong>clude:<br />

• miscarriage<br />

• pre-term (premature) delivery<br />

• stillbirth<br />

• <strong>in</strong>trauter<strong>in</strong>e growth restriction (IUGR) or ‘small for dates’<br />

• low birth weight<br />

• placental abruption<br />

• reduction <strong>in</strong> breast milk production<br />

• Sudden Infant Death Syndrome (SIDS or ‘cot death’).<br />

Babies born to heavy smokers may also exhibit m<strong>in</strong>or signs of withdrawal,<br />

<strong>in</strong>clud<strong>in</strong>g ‘jitter<strong>in</strong>ess’ <strong>in</strong> the per<strong>in</strong>atal period (Scottish Executive 2003).<br />

Children of smokers also suffer more respiratory <strong>in</strong>fections <strong>in</strong> childhood<br />

and adolescence.<br />

Effects of alcohol<br />

Alcohol use dur<strong>in</strong>g pregnancy may potentially affect fetal bra<strong>in</strong><br />

development at any gestation. At all po<strong>in</strong>ts along the cont<strong>in</strong>uum from<br />

occasional light dr<strong>in</strong>k<strong>in</strong>g to regular heavy dr<strong>in</strong>k<strong>in</strong>g there is conflict<strong>in</strong>g<br />

evidence as to the possibility of damag<strong>in</strong>g effects on the fetus<br />

(Mounteney 1999). It is important to remember that a ‘safe’ level of<br />

alcohol use <strong>in</strong> pregnancy has not been established.<br />

<strong>Substance</strong> <strong>Misuse</strong> <strong>in</strong> <strong>Pregnancy</strong><br />

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