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Substance Misuse in Pregnancy - NHS Lothian

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There may be placental <strong>in</strong>sufficiency <strong>in</strong> pregnancies of drug-us<strong>in</strong>g women,<br />

lead<strong>in</strong>g to an <strong>in</strong>creased risk of <strong>in</strong>trapartum hypoxia, fetal distress and<br />

meconium sta<strong>in</strong><strong>in</strong>g (Department of Health 1999). Meconium aspiration is<br />

common and is associated with fetal distress secondary to periods of<br />

<strong>in</strong>tra-uter<strong>in</strong>e drug withdrawal. Some babies will be growth restricted so<br />

there should be careful surveillance dur<strong>in</strong>g labour. Maternity staff should<br />

follow hospital guidel<strong>in</strong>es for obstetric and neonate management for<br />

meconium sta<strong>in</strong><strong>in</strong>g.<br />

High dose benzodiazep<strong>in</strong>e use <strong>in</strong> the mother can result <strong>in</strong> the newborn<br />

show<strong>in</strong>g signs of <strong>in</strong>toxication at birth that <strong>in</strong>clude: poor suck<strong>in</strong>g, poor<br />

reflexes, hypotonia (low muscle tone), hypothermia (low body<br />

temperature), a feeble cry and low APGAR scores. Severely affected<br />

neonates may require vigorous resuscitation at birth because of<br />

respiratory depression. Women who are anxious about childbirth should be<br />

warned not to ‘self medicate’ with non-prescribed benzodiazep<strong>in</strong>es (e.g.<br />

Valium®) before they admit themselves for delivery.<br />

Please note: Labour ward staff must not use naloxone (an opiate<br />

antagonist) to reverse opioid <strong>in</strong>duced respiratory depression <strong>in</strong> neonates<br />

as this will <strong>in</strong>duce an abrupt opiate withdrawal crisis. Use supportive<br />

measures or ventilation if necessary.<br />

Postpartum care <strong>in</strong> hospital<br />

After delivery, the labour ward midwife should liaise with staff <strong>in</strong> the<br />

postnatal ward to ensure cont<strong>in</strong>uity of care. The key midwife <strong>in</strong> the<br />

community should also be <strong>in</strong>formed of the delivery. This is particularly<br />

important if the woman has delivered pre-term. Maternity staff provid<strong>in</strong>g<br />

<strong>in</strong>trapartum care should complete the pregnancy outcome form<br />

(substance misuse) (see appendix 9).<br />

All known drug dependent women are asked to stay <strong>in</strong> hospital for three<br />

days (72 hours) follow<strong>in</strong>g the birth of their baby. This is because the<br />

baby needs to be observed for signs and symptoms of Neonatal<br />

Abst<strong>in</strong>ence Syndrome (NAS), which normally develop with<strong>in</strong> this time<br />

period (see section on NAS for further <strong>in</strong>formation, page 43).<br />

<strong>Substance</strong> <strong>Misuse</strong> <strong>in</strong> <strong>Pregnancy</strong><br />

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