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Acute Kidney Injury

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Prevention of<br />

Contrast-Induced Nephropathy<br />

• Identify high risk patients<br />

• Volume expand with isotonic sodium chloride or sodium<br />

bicarbonate<br />

‣ Optimal fluid composition and timing and rate of fluid<br />

administration remain uncertain<br />

• Use low osmolar or iso-osmolar contrast in high-risk population<br />

• N-acetylcysteine<br />

‣ Although data are inconclusive, NAC is inexpensive and safe<br />

• Discontinue NSAIDs and vasoconstrictors

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