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CLARK Prescription Drug Abuse - Misuse Neurobiology Epidemiology EBPs

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Addiction is a Chronic Brain Disease<br />

<strong>Drug</strong> and alcohol addiction are chronic &<br />

relapsing diseases involving the brain’s<br />

reward and control circuitries.<br />

Neuroadaptations that follow chronic drug<br />

exposure ultimately serve to impair the<br />

function of brain regions involved with<br />

motivation and self-control.<br />

Substance dependence disorders have<br />

relapse rates similar to those of<br />

hypertension, diabetes, and asthma.<br />

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