CLARK Prescription Drug Abuse - Misuse Neurobiology Epidemiology EBPs

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Addiction is a Chronic Brain Disease <strong>Drug</strong> and alcohol addiction are chronic & relapsing diseases involving the brain’s reward and control circuitries. Neuroadaptations that follow chronic drug exposure ultimately serve to impair the function of brain regions involved with motivation and self-control. Substance dependence disorders have relapse rates similar to those of hypertension, diabetes, and asthma. 10
Addiction is like other chronic diseases… It changes biology It is preventable It is treatable Diabetes Treatment Strategies: Lifestyle + Medication 11
Page 2 and 3: Prescription Drug Abuse & Misuse: N
Page 4 and 5: Secretary Kathleen Sebelius U.S. De
Page 6 and 7: Prescription Drugs Abuse & Misuse:
Page 8 and 9: Topics Neurobiology Epidemiology EB
Page 12 and 13: Movement Motivation Dopamine Addict
Page 14 and 15: Slide courtesy of NIDA 14
Page 16 and 17: Dopamine & Exogenous Opioids: Hyper
Page 18 and 19: Other Neurotransmitter Systems Scie
Page 20 and 21: Opioid Binding Sites Adapted from N
Page 22 and 23: One Size Does Not Fit All: Addictio
Page 24 and 25: Topics Neurobiology Epidemiology Tr
Page 26 and 27: Past Month Nonmedical Use of Types
Page 28 and 29: Source Where Pain Relievers Were Ob
Page 30 and 31: Past Month and Past Year Heroin Use
Page 32 and 33: Past Year Initiates of Specific Ill
Page 34 and 35: Substances for Which Most Recent Tr
Page 36 and 37: Percentage of ED visits involving n
Page 38 and 39: Opioid Related Emergency Department
Page 40 and 41: Topics Neurobiology Epidemiology EB
Page 42 and 43: ROSC: A Way to Better Health for Al
Page 44 and 45: ROSC Framework Provides a coordinat
Page 46 and 47: One Size Does Not Fit All: Evidence
Page 48 and 49: Medication Assisted Treatment MAT i
Page 50 and 51: EBP: Rehabilitation & Therapeutic M
Page 52 and 53: EB Treatment is Complicated: Interd
Page 54 and 55: EBP Opioid Overdose Toolkit Over 23
Page 56 and 57: EBP Treatment Protocols and KAP Key
Page 58 and 59: EBP Consensus Guidelines (in proces
Page 60 and 61:
EBP Literature Reviews September 20
Page 62 and 63:
EBP: SBIRT’s Return-on-Investment
Page 64 and 65:
SAMHSA Block Grants (Dollars in Tho
Page 66 and 67:
Implementation of National Action P
Page 68 and 69:
Key Takeaways of National Action Pl
Page 70 and 71:
“Advancing Access to Addiction Me
Page 72:
THANK YOU! Westley.Clark@samhsa.hhs
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CLARK Prescription Drug Abuse - Misuse Neurobiology Epidemiology EBPs

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