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COMBI 40+ ABI Auditory Brainstem Implant - Med-El

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<strong>COMBI</strong> <strong>40+</strong> <strong>ABI</strong><br />

<strong>Auditory</strong> <strong>Brainstem</strong> <strong>Implant</strong><br />

The <strong>COMBI</strong> <strong>40+</strong> <strong>Auditory</strong> <strong>Brainstem</strong><br />

<strong>Implant</strong> (<strong>ABI</strong>) is a highly advanced<br />

technological system for individuals<br />

with hearing loss due to a<br />

nonfunctional auditory nerve, such as<br />

in cases of Neurofibromatosis Type 2<br />

(NF2). Bypassing the inner ear and<br />

auditory nerve, the <strong>COMBI</strong> <strong>40+</strong> <strong>ABI</strong><br />

allows high-rate stimulation of the<br />

cochlear nucleus (CN) and can<br />

provide recipients a variety<br />

of sound sensations.<br />

N e u ro f i b ro m a t o s i s<br />

Type 2 (NF2)<br />

Neurofibromatosis Type 2 (NF2), also known<br />

as Bilateral Acoustic NF (BAN), is a rare<br />

genetic disorder that affects approximately 1<br />

in 40,000 individuals. NF2 can either be<br />

inherited or occur spontaneously without any<br />

apparent familial history. The gene defect was<br />

isolated in 1993 to the merlin tumor<br />

suppressor area of chromosome 22. NF2 is<br />

characterized by non-malignant tumor growth,<br />

primarily in the brain and spinal cord. A<br />

hallmark of NF2 is the presence of bilateral<br />

acoustic neuromas, which originate in the<br />

vestibular nerve and often invade the adjacent<br />

auditory nerve, causing progressive hearing<br />

loss and ultimately deafness. <strong>Auditory</strong><br />

<strong>Brainstem</strong> <strong>Implant</strong>s stimulate the cochlear<br />

nucleus (CN) and have the potential to<br />

provide NF2 patients hearing sensations that<br />

assist with sound awareness and<br />

communication.<br />

• implant housing<br />

containing implant circuitry<br />

and a powerful microchip<br />

• active electrode array<br />

placed on the cochlear nucleus<br />

during implantation

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