Pit and Fissure Sealants in the Prevention of Dental Caries in ...

––– Azarpazhooh –––
Citation: Pinar A, Sepet E, Aren G, Bolukbasi N, Ulukapi H, Turan N. Clinical performance of sealants with and
without a bonding agent. Quintessence Int 2005; 36(5):355–60.
Population: 30 schoolchildren with all permanent first molars sound and unsealed (n =120 teeth)
• Age: 8–10 years
• Sex: Not mentioned
• Location: Pediatric dentistry clinic, faculty of dentistry, University of Istanbul, Istanbul, Turkey
• Representative of schoolchildren with low socioeconomic status and high risk of caries
Intervention: Split-mouth design using 4 molars from each child; n = 60 teeth, with 1 maxillary and 1 mandibular
molar from each child receiving sealant (Fissurit F, Voco/Cuxhaven) with a bonding agent
Control: n = 60 contralateral teeth, which received only sealant (Fissurit F, Voco/Cuxhaven)
Outcomes: Assessed at 3, 6, 12 and 24 months (only data from 12 and 24 months were abstracted)
• At 12-month follow-up, n = 48 teeth in each group; total loss to follow-up 20%
• At 24-month follow-up, n = 44 teeth in each group; total loss to follow-up 27%
Marginal integrity (clinically acceptable) at 12- and 24-month follow-ups:
• Significant difference in each group relative to baseline
• Nonsignificant difference between experimental groups
• Sealant + bonding agent: 83.3% and 79.5% at 12 and 24 months, respectively
• Sealant only: 81.2% and 77.2% at 12 and 24 months, respectively
• No marginal discoloration at 12- and 24-month follow-ups
• Significant difference in each group relative to baseline
• Nonsignificant difference between experimental groups
• Sealant + bonding agent: 81% and 75% at 12 and 24 months, respectively
• Sealant only: 79% and 72% at 12 and 24 months, respectively
Retention rate at 12- and 24-month follow-ups:
• Significant difference in each group relative to baseline
• Nonsignificant difference between experimental groups
• Sealant + bonding agent: 83% and 79% at 12 and 24 months, respectively
• Sealant only: 81% and 75% at 12 and 24 months, respectively
Authors’ Conclusion: At 2 years after application, placement of a bonding agent under sealants did not significantly
affect the clinical success of sealants.
Critical Appraisal:
• No placebo control for caries incidence
• No power calculation
• 27% loss to follow-up after 2 years
Level of Evidence, Grade of Recommendation and Score on “Checklist to Assess Evidence of Efficacy of Therapy
or Prevention”: Level I; grade A for caries protection and retention rate of both techniques for sealing teeth;
score 13.5/16
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