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Seasonal Influenza <strong>Vaccine</strong>s<br />
Potency Measurements<br />
� Potency measurements require reference immunoreagents<br />
� Type/Subtype matched antisera<br />
� Type/Subtype matched antigen (virus) HA reference standard<br />
� SRID assay features<br />
� Antiserum is incorporated into agarose matrix<br />
� Samples are solubilized with detergent and allowed to diffuse<br />
into the agarose<br />
� A zone of immunoprecipitin forms where the antibody-antigen<br />
complex is no longer soluble