ANNUAL REPORT 2009-2010 - University of Toronto Department of ...

ANNUAL REPORT 2009-2010
P-C1 GENERATION OF SOLUBLE FORMS OF ENDOGLIN FOR STRUCTURAL
STUDIES
Allison Gregory [G] (1,2,3), Guoxiong Xu (1,2,3), Luca Jovine (4), Michelle Letarte (1,2,3).
(1) Molecular Structure and Function Program, Hospital for Sick Children, Toronto, (2)
Immunology Department, University of Toronto, (3) Heart and Stroke Richard Lewar Center of
Excellence, (4) Center for Structural Biochemistry, Karolinska Institutet, Sweden.
P-C2 ANGIOGENIC RESPONSE OF THE HUMAN PLACENTA TO HEPARIN:
IMPLICATIONS FOR THE PREVENTION OF PRE-ECLAMPSIA
Mara Sobel [R] (1), Sascha Drewlo (2), John Kingdom (1,2)
(1) Department of Obstetrics & Gynaecology and (2) Samuel Lunenfeld Research Institute,
Mount Sinai Hospital, University of Toronto
P-C3 ROLE OF FACTOR INHIBITING HIF-1 (FIH-1) IN THE SELECTIVE
REGULATION OF HIF-1 TARGET GENES IN PREECLAMPSIA
Antonella Racano[G](1,2), Tullia Todros (4), Isabella Caniggia (1,2,3).(1) Samuel Lunenfeld
Research Institute, Mount Sinai Hospital; Depts. of (2) Physiology & (3) Obstetrics and
Gynaecology, University of Toronto; (4) Dept. of Obstetrics and Gynaecology, University of
Turin, Turin, Italy.
P-C4 HEPARIN ELEVATES SFLT-1 SECRETION AND IMPAIRS VILLOUS
TROPHOBLAST PHYSIOLOGY IN A DOSE-DEPENDENT MANNER:
IMPLICATIONS FOR THE PREVENTION OF SEVERE PREECLAMPSIA
Sascha Drewlo [PD](1), Khrystyna Levytska(1), Dora Baczyk(1), Mara Sobel (2), John
Kingdom (1,2).
(1)Samuel Lunenfeld Research Institute, Mount Sinai Hospital, University of Toronto,
(2)Obstetrics & Gynaecology, Mount Sinai Hospital, University of Toronto
P-C5 A STORY OF LIFE AND DEATH: THE DUAL ROLE OF MTD/BOK IN
TROPHOBLAST CELL FATE
Jocelyn Ray[G](1), Julia Garcia(1), Yuan Wu(1), Tullia Todros(2) Andrea Jurisicova(1),
Isabella Caniggia(1).
(1) Departments of Obstetrics/Gynaecology & Physiology, SLRI, Mount Sinai Hospital,
University of Toronto, (2) Dept. of Obstetrics and Gynecology, University of Turin, Turin, Italy.
P-D1 FLUORESCENT IN SITU HYBRIDIZATION (FISH) IS AN EFFECTIVE TOOL
TO DETECT UNSUSPECTED TRISOMIES IN HYDROPIC GESTATIONS
Raheela Siddiqui [R](1), Kathy Chun (2), Zeina Ghorab (1), Nadia Ismiil (1), Mahmoud Khalifa
(1), Sharon Nofech-Mozes (1), Raymond Osborne (3), Reda Saad (1), Christopher Sherman (1),
Valérie Dubé (1).
(1) Department of Pathology, Sunnybrook HSC, (2) Genetics Program, North York General
Hospital, (3) Division of Gynecologic Oncology, Sunnybrook Health Sciences
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