Debunking Human Health Risk, APPENDIX D - LBAMspray.com
Debunking Human Health Risk, APPENDIX D - LBAMspray.com
Debunking Human Health Risk, APPENDIX D - LBAMspray.com
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LIGHT BROWN APPLE MOTH ERADICATION PROJECT<br />
<strong>APPENDIX</strong> D<br />
DRAFT PEIR<br />
HUMAN HEALTH RISK ASSESSMENT<br />
D3.1.2<br />
Carriers and Dispersants of Chlorpyrifos<br />
DuraGuard ® ME and Dursban ® 4E are chlorpyrifos-containing products approved for the control<br />
or prevention of LBAM at nurseries and/or in crop production areas. The DuraGuard ® ME<br />
material safety datasheet (MSDS) (Whitmire MicroGen 2001) does not list any specific inert<br />
ingredients, noting only that these <strong>com</strong>prise 80% of the product, with chlorpyrifos making up the<br />
remaining 20%. The Dursban ® 4E MSDS lists xylene range aromatic solvents and emulsifiers as<br />
<strong>com</strong>prising 55.1% of the product, and provides CAS numbers for xylenes, ethyl toluenes,<br />
trimethyl benzenes, and ethylbenzene. Specific quantities are not given for these inert ingredients<br />
(DowElanco 1998). In the following discussion, information on 1,2,4-trimethylbenzene is<br />
provided in lieu of general information on the category of <strong>com</strong>pounds known as<br />
trimethylbenzenes. Both 1,2,4-trimethylbenzene and ethylbenzene are also <strong>com</strong>ponents of the<br />
permethrin formulation (Permethrin E-Pro) proposed for use in both the No Program Alternative<br />
and the MMA Program Alternative.<br />
D3.1.2.1<br />
Environmental Fate and Chemistry of Inert Ingredients<br />
D3.1.2.1.1 Chemical and Physical Properties of Inert Ingredients<br />
1,2,4-TRIMETHYLBENZENE<br />
1,2,4-trimethylbenzene (molecular formula C 9 H 12 , CAS number is 95-63-6) is used as an<br />
intermediate in the manufacture of dyes, pharmaceuticals, and the synthesis of the chemical<br />
pseudocumidine, although it’s primary industrial use is as a solvent and paint thinner (Hazardous<br />
Substances Database [HSDB] 2009). Key chemical and physical properties of 1,2,4-<br />
trimethylbenzene are given in Table D3-6. The structure of 1,2,4-trimethylbenzene is given on<br />
Figure D3-2.<br />
Table D3-6<br />
Chemical and Physical Properties of 1,2,4-trimethylbenzene<br />
Property<br />
Parameter<br />
Molecular weight, grams 120.191<br />
Color and state<br />
Clear colorless liquid<br />
Boiling point<br />
168.89ºC<br />
Solubility in water 57 mg/L at 25ºC<br />
Log octanol-water partition coefficient (KOW) 3.78<br />
Vapor pressure at 25ºC<br />
2.10 mmHg<br />
Henry’s Law Constant at 20ºC<br />
6.16 x 10 -3 atm m 3 /mol<br />
Source:<br />
HSDB 2009<br />
Figure D3-2<br />
Structure of 1,2,4-Trimethylbenzene (from National Library of Medicine)<br />
D3-14 App D_HHRA_508.doc JULY 2009
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