Matching in case control studies - The INCLEN Trust

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Matched analysis by set (Pairs of 1 case / 1 control) • Discordant pairs • Cases and controls have different exposures • ad’s and bc’s: input to the calculation Cases Controls Total Exposed 1 0 1 Non-exposed 0 1 1 Total 1 1 2 Positive association Cases Controls Total Exposed 0 1 1 Non-exposed 1 0 1 Total 1 1 2 Negative association Matched analysis
The Mantel-Haenszel odds ratio... OR M-H = a i .d i ) / Ti] b i .c i ) / Ti] Matched analysis
Page 1 and 2: Arranged marriage Matching in case
Page 3 and 4: Key elements • The concept of mat
Page 5 and 6: Matching: concept • Confounding i
Page 7 and 8: Consequences.... • The problem:
Page 9 and 10: Types of matching strategies • Fr
Page 11 and 12: Matching: True statements Matching
Page 13 and 14: Example: Risk factors for microspor
Page 15: Matched analysis by set (Pairs of 1
Page 19 and 20: …and the analysis can be done wit
Page 21 and 22: The old 2 x 2 table... Cases Contro
Page 23 and 24: The Mac Nemar chi-square Chi 2 McN=
Page 25 and 26: Matching: Inconvenience • Must be
Page 27 and 28: Hidden matching (“Crypto-matching
Page 29 and 30: Breaking the match • Rationale

Matching in case control studies - The INCLEN Trust

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