Matching in case control studies - The INCLEN Trust
Matching in case control studies - The INCLEN Trust
Matching in case control studies - The INCLEN Trust
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<strong>Match<strong>in</strong>g</strong> with a variable associated with<br />
exposure, but not with illness<br />
(Overmatch<strong>in</strong>g)<br />
• Reduces variability<br />
• Increases the number of concordant pairs<br />
• Has deleterious consequences:<br />
• If matched analysis: reduction of power<br />
• If match broken: Odds ratio biased towards one<br />
Pro and cons
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