Matching in case control studies - The INCLEN Trust
Matching in case control studies - The INCLEN Trust
Matching in case control studies - The INCLEN Trust
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Analysis of matched <strong>case</strong> <strong>control</strong> <strong>studies</strong><br />
with more than one <strong>control</strong> per <strong>case</strong><br />
• Sort out the sets accord<strong>in</strong>g to the exposure<br />
status of the <strong>case</strong>s and <strong>control</strong>s<br />
Example for 1 <strong>case</strong> / 2 <strong>control</strong>s<br />
Sets with <strong>case</strong> exposed: +/++, +/+-, +/--<br />
Sets with <strong>case</strong> unexposed: -/++, -/+-, -/--<br />
• Count reconstituted <strong>case</strong>-<strong>control</strong> pairs for<br />
each type of set<br />
• Multiply the number of discordant pairs <strong>in</strong><br />
each type of set by the number of sets<br />
• Calculate odds ratio us<strong>in</strong>g the f/g formula<br />
Matched analysis
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