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Vascular intervention

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Catheter-directed thrombolysis for<br />

lower extremity DVT: Report of a<br />

national multicenter registry<br />

Mewissen MW, Seabrook GR, Meissner MH, et al. Radiology 211:39-49, 1999.<br />

The Venous Registry described treatment of 303 limbs in 287<br />

patients with acute and chronic lower extremity DVT treated with<br />

urokinase (mean, 7.8 million U and 53.4 hours), the overall complete<br />

and partial lysis rate was 83% with a 1-year patency rate of 60%.<br />

Patients with complete lysis had higher 1-year patency rate (79%).<br />

Iliofemoral thromboses fared significantly better than<br />

femoropopliteal thromboses (no iliac involvement) with 1-year<br />

patency rates of 79% and 64%, respectively.

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