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Technology Push vs. Market Pull - CiPoC

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<strong>Technology</strong> <strong>Push</strong> <strong>vs</strong>. <strong>Market</strong> <strong>Pull</strong><br />

<strong>CiPoC</strong>


Major Points for the Day<br />

• It’s not just the science and/or technology, much of which is<br />

already available anyway for exploitation and doesn’t need<br />

reinvention…(Providers)<br />

• There are lots of opportunities and unsolved problems with<br />

commercial potential! (Customers)<br />

• There are investors and sponsors that recognize these<br />

opportunities and are willing to share risk given an attractive value<br />

proposition (Payers, at least initially)<br />

Our goal for the day<br />

• Initiate an interdisciplinary network with the long-term goal of<br />

facilitating development and commercialization of “PoC/A”<br />

technologies…..<br />

<strong>CiPoC</strong>


It’s not just the science…<br />

A recent post on the <strong>Technology</strong> Transfer Tactics website cited a survey of tech<br />

transfer professionals. There was only one survey question: "What are the top<br />

three reasons for failure of university startup companies" There were the<br />

typical reasons you might expect like “management failure” and “lack of capital”;<br />

and there were some reasons related to culture and policy in the international<br />

entrepreneurial stage. But there was one that was either tied directly or indirectly to<br />

several of the others, and that was "Innovation does not meet a commercial<br />

need…."<br />

(http://www.technologytransfertactics.com/content/2010/07/14/survey-suggests-top-<br />

10-reasons-university-start-ups-fail/ )<br />

This makes a lot of sense to me. I would rather have a well-defined<br />

customer base with a recognized need than some high-tech solution<br />

looking for a problem. As an engineer, coming up with a solution is<br />

easier than finding the problem, figuring who is willing to pay to<br />

solve it and how much that solution is worth.<br />

<strong>CiPoC</strong>


It’s not just the science…<br />

<strong>CiPoC</strong>


It’s not just the science…<br />

Long <strong>Technology</strong> <strong>Push</strong>… Super Strong <strong>Market</strong> <strong>Pull</strong><br />

• Diabetes patients > 300 M in<br />

2030<br />

→20 B $ 2015<br />

• Clear and unequivocal clinical<br />

benefit<br />

• Clear and unequivocal<br />

economic benefit<br />

• Price – Performance<br />

Improvements (cost)<br />

≈ 11-12 B $ 2012<br />

Home use early 1980’s<br />

• <strong>Market</strong> expansion<br />

Hospital/office use early 1970’s<br />

Clark, L., Jr.; Lyons, C. Ann. NY Acad. Sci. 1962, 102, 29.<br />

www.k9diabetes.com<br />

<strong>CiPoC</strong>


It’s not just the science…<br />

Unsuccessful <strong>Technology</strong> (Reinvention) <strong>Push</strong>….<br />

Pelikan Technologies, Inc. – An HP Diagnostics (Agilent) Spinout from 2001…<br />

…liquidated as of 28-09-2011<br />

VS.<br />

• Hi-tech Pelikan Sun electronic lancet<br />

• $100 M Development Cost<br />

• $200 for instrument (not original price!)<br />

• $15 for 100 lancets (2 wheels) –<br />

15 cents per piece<br />

• Low-tech standard blood lancet<br />

• Development Cost<br />

• 100 lancets for $4.10 (4.1 cents<br />

per piece on Amazon.com!)<br />

“…(The) Children with Diabetes web site has a number of user reviews on<br />

this product. Most said it was not worth it, that the lancets are on a wheel<br />

and cannot be used twice, that the tester is large and not as easy to use as<br />

most blood testing devices. The positive comment is that it is virtually pain<br />

free. I test 6-8 times per day and have never developed calluses, infections<br />

or bruises on my fingers, so some of the marketing claims for the Pelikan are<br />

really BOGUS”….<br />

<strong>CiPoC</strong>


It may just be the science (for now)….…<br />

Hand held<br />

ACA<br />

NGS on a<br />

chip<br />

The $10 million top prize will be awarded to the team that<br />

develops a mobile platform that most accurately<br />

diagnoses Siri, M.D. a set of 15 diseases across 30 consumers<br />

in three days. Teams must also deliver this information in<br />

a way that provides a compelling consumer experience<br />

while capturing real time, critical health metrics such as<br />

blood pressure, respiratory rate and temperature. The<br />

winning solutions will enable consumers in any location to<br />

quickly and effectively assess health conditions, determine<br />

if they need professional help and answer the question,<br />

“What do I do next” (when it comes to their health).<br />

http://www.qualcommtricorderxprize.org<br />

http://www.bbc.co.uk/news/technology-16518171<br />

<strong>CiPoC</strong>


It’s not just the science…<br />

<strong>CiPoC</strong>


There are lots of opportunities and unsolved problems…<br />

• Aging will be a major theme. The number of elderly will explode,<br />

and perhaps surprisingly, 90% of this growth will take place in<br />

emerging markets.<br />

• Due mainly to explosive growth in many emerging markets, the world<br />

will experience its largest economic growth ever, and global real<br />

purchasing power will have quadrupled by 2050.<br />

• The world will experience significant, but decelerating population<br />

growth. Meanwhile, people will continue their net migration towards<br />

cities while many rural areas will get depopulated.<br />

• Global knowledge and innovation will continue to evolve<br />

exponentially, and by 2050, our combined commercially/technically<br />

useful knowledge will be 40-50 times as large as in 2010.<br />

www.supertrends.com<br />

• More and more industries will essentially become information<br />

technologies, and this will vastly accelerate their development pace.<br />

• We will not run out of any commodities, but we may experience<br />

temporary shortages of energy and metals due to the explosive growth<br />

in emerging markets<br />

• New technologies will provide the solutions to environmental<br />

problems, and many of these will be rapidly reduced as our<br />

<strong>CiPoC</strong><br />

wealth and<br />

technical acumen grow.


There are lots of opportunities and unsolved problems…<br />

Healthcare Sector….<br />

• Aging population with fewer to pay<br />

• Infectious medicine<br />

Bakterier på hospitaler dræber patienter<br />

Mandag the 27. Februar 2012, 05:00... patienter, hvor det er dokumenteret, at<br />

de er døde som følge af skader efter at være blevet smittet med tarmbakterien<br />

med det videnskabelige navn Clostridium difficile CD027. I samme periode er<br />

antallet af smittede næsten fordoblet fra 598 i 2009 til 1.059 i 2011, fremgår det<br />

af tal fra ...<br />

<strong>CiPoC</strong>


There are lots of opportunities and unsolved problems…<br />

Environmental Sector….<br />

• 9 x 10 9 in 2050<br />

• H 2 O<br />

Forurenet vand skal varsles hurtigere<br />

Onsdag the 9. November 2011, 03:00... laboratoriums analyser viser<br />

bakterier i drikkevandet, skal der fremover reageres prompte, ...<br />

grænseværdierne for eksempelvis bakterier i drikkevandet. Et laboratorium<br />

må ikke længere ... borgerne skal have, hvis deres drikkevand er forurenet.<br />

Det kan for ... rådgives om, hvordan man skal koge sit vand, før man bruger<br />

... 2010 leverede rent drikkevand til forbrugerne. ...<br />

<strong>CiPoC</strong>


There are lots of opportunities and unsolved problems…<br />

Agriculture and Foodstuff Sector….<br />

• 9 x 10 9 in 2050<br />

• Protecting the food-supply chain<br />

Salmonella tre gange på en måned<br />

Mandag the 20. Februar 2012, 15:04 Den 27.<br />

januar advarede Fødevarestyrelsen mod<br />

salmonella i et parti hakket svine- og ... er tredje<br />

gang, at de finder salmonella i deres produkter,<br />

siger Kim Vandrup ... at forhindre de hyppige fund<br />

af salmonella, der alle gange er blevet opdaget ...<br />

råvarer ind, hvor der har været salmonella, som<br />

de ikke har ...<br />

<strong>CiPoC</strong>


Investors and sponsors…<br />

Understanding what investors and sponsors want….<br />

• Global knowledge and innovation will continue to evolve exponentially<br />

• Value Propositions (big differences between market sectors)<br />

<strong>CiPoC</strong>


Investors and sponsors…<br />

Few, expensive<br />

tests<br />

Many, cheap tests<br />

<strong>CiPoC</strong>


<strong>CiPoC</strong>


“Risk comes from not knowing<br />

what you're doing.”<br />

“In the business world, the<br />

rearview mirror is always clearer<br />

than the windshield.”<br />

<strong>CiPoC</strong>

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