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English - Global Alliance to Eliminate Lymphatic Filariasis

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REPORT OF THE 6 TH GAELF MEETING, JUNE 2010<br />

Keynote Addresses<br />

Chair: Professor Jong-Yil Chai<br />

Seoul National University College of Medicine<br />

The first session of the conference,<br />

chaired by Professor Jong-Yil Chai,<br />

described the successful elimination of LF<br />

in Korea.<br />

A his<strong>to</strong>ry of a country elimination<br />

Professor Han-Jong Rim, Emeritus<br />

Professor at Korea University College of<br />

Medicine, reviewed the his<strong>to</strong>ry of LF<br />

elimination in Korea, which can be<br />

considered in three distinct phases [1].<br />

During the first phase, 1920-1945, LF was<br />

initially recognized as an endemic public<br />

health problem and was found <strong>to</strong> be<br />

caused only by Brugia malayi.<br />

The period 1951-1979 was one of<br />

investigation and surveillance. Three<br />

major endemic areas were identified: Jeju<br />

Island; the southwest coastal area; and an<br />

area in the southeast, which extended<br />

inland. Epidemiologic investigations were<br />

conducted in all of these areas, where<br />

microfilaremia prevalence ranged from 1<br />

<strong>to</strong> 22%. These investigations showed that<br />

B. malayi was nocturnally periodic and the<br />

principal vec<strong>to</strong>rs were Aedes <strong>to</strong>goi, in<br />

coastal areas, and Anopheles sinensis,<br />

inland. No LF transmission was detected in<br />

the central part of the country, which is<br />

mountainous. Persons infected with B.<br />

malayi were treated selectively with<br />

diethylcarbamazine (DEC), beginning with<br />

low doses <strong>to</strong> minimize adverse reactions.<br />

Certain aspects of traditional life were<br />

identified as facilitating transmission,<br />

including the habit of gathering water<br />

during the evenings, and the thatched<br />

roofs, which provided resting places for A.<br />

<strong>to</strong>goi.<br />

Prevalence of infection with soil-transmitted helminthes and gross national product, Republic<br />

of Korea, 1969-1989<br />

15

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