Model Answers Microbiology Written examinations 2007 - RCPA
Model Answers Microbiology Written examinations 2007 - RCPA
Model Answers Microbiology Written examinations 2007 - RCPA
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Common CSF findings<br />
Viral<br />
Meningitis<br />
Bacterial<br />
Menignitis<br />
Cryptococcal<br />
meningitis<br />
TB<br />
meningitis<br />
Viral<br />
encephalitis<br />
Protein Glucose Cells Gm<br />
stain<br />
Bacterial<br />
culture<br />
Comments<br />
No or No Predominately Neg Neg Can do<br />
Slightly<br />
Lymphs<br />
enterovirus<br />
raised<br />
(some pdys<br />
PCR<br />
Raised<br />
Raised<br />
Raised<br />
No or<br />
raised<br />
day 1-3)<br />
Decreased May be pos,<br />
predominately<br />
pdys<br />
No or<br />
decreased<br />
Predominately<br />
lymphs<br />
Decreased Predominately<br />
lymphs<br />
No<br />
Predominately<br />
lymphs<br />
May be<br />
positive<br />
May be<br />
pos (Abs<br />
suggested)<br />
Neg Neg Can do<br />
India ink<br />
stain &<br />
CSF<br />
crypto AG<br />
Neg<br />
TB<br />
culture<br />
slow often<br />
6-8 weeks<br />
Can do<br />
AFB often<br />
neg TB<br />
PCR or<br />
LCX<br />
Neg Neg Can do<br />
HSV PCR<br />
<br />
Bacterial antigens no longer done – poor sensitivity and specificity.<br />
Extra tests<br />
Rarely useful unless abnormal protein/glucose/cell count<br />
<br />
<br />
<br />
<br />
<br />
<br />
<br />
<br />
<br />
<br />
crytpococcal antigen<br />
India ink stain (Cryptococcus)<br />
TB PCR/LCX<br />
AFB stain – rarely positive, need a lot of cells<br />
TB culture (6-8 weeks)<br />
HSV 1 & 2 PCR<br />
Enterovirus PCR<br />
JC virus PCR<br />
Meningococcal PCR<br />
Syphilis serology e.g. RPR, PTHA
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