Pharmacological Management of Acute Kidney Injury

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Principles of Management 1. Making the patient safe, 2. treating life-threatening metabolic disturbances, irrespective of the cause 3. Non-dialytic treatment measures – drugs, nutrition, fluid replacement 4. Initiating renal replacement therapy (RRT) when appropriate 5. Investigating and treating the primary aetiology – pre-renal, renal and post-renal
Clinical Definitions Acute v Chronic Renal Failure Reversible Irreversible v Sudden Insidious onset v
Page 1 and 2: Pharmacological Management of Acute
Page 4 and 5: RESUSCITATE
Page 6 and 7: It’s costly! • Only modest impr
Page 8 and 9: Uraemia • Is generally used to de
Page 10 and 11: GFR and creatinine
Page 14 and 15: Acute Renal Failure • Abrupt decl
Page 16 and 17: Serum Creatinine = 150 umol/l Weigh
Page 18 and 19: Is he sick?
Page 20 and 21: Treating Life-threatening Metabolic
Page 22: A 63 year old lady presents with pr
Page 25 and 26: Treatment of Fluid Overload • Avo
Page 27 and 28: Treatment of Acidosis • NaHCO 3 1
Page 29 and 30: Acetate vs. Bicarbonate dialysis Li
Page 31 and 32: Pre - renal A Comparison of Albumin
Page 33 and 34: Bleeding Diathesis • Haematocrit
Page 35 and 36: Prevention of radiocontrast-induced
Page 37 and 38: Fenoldopam Crit Care Med. 2005 Nov;
Page 39 and 40: Atrial Natriuretic Peptide for Mana
Page 41 and 42: Diuretics • Basis : wash away the
Page 43 and 44: Growth factors • Basis : After su
Page 45 and 46: Nutrition in Acute Renal Failure
Page 47 and 48: Renal Biopsy in ARF • Generally n
Page 49: Acknowledgements • To Prof. Ken F

Pharmacological Management of Acute Kidney Injury

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