Pharmacological Management of Acute Kidney Injury

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Anti-inflammatory agents • Basis : The ischaemic kidney produces a number <strong>of</strong> inflammatory mediators; tubular cells participate in immune and inflammatory reactions • Conclusion :Antibodies to ICAM-1, antineutrophil agents are still at trial level
Nutrition in <strong>Acute</strong> Renal Failure • Nutrition should not be compromised to minimize azotaemia • When ARF is isolated energy requirements are probably not increased. • >15%-20% in patients on IHD • Recommendations • Calories 30kcal/kg BW/day + adjustment factors • 70% carbohydrates 30% lipids • Proteins (on dialysis) 1.1-1.2g/kg BW/day (otherwise 0.8g/kg/day) • Micronutrients? Se, vitamin E • Enteral preferable • TPN if necessary.
Page 1 and 2: Pharmacological Management of Acute
Page 4 and 5: RESUSCITATE
Page 6 and 7: It’s costly! • Only modest impr
Page 8 and 9: Uraemia • Is generally used to de
Page 10 and 11: GFR and creatinine
Page 12 and 13: Principles of Management 1. Making
Page 14 and 15: Acute Renal Failure • Abrupt decl
Page 16 and 17: Serum Creatinine = 150 umol/l Weigh
Page 18 and 19: Is he sick?
Page 20 and 21: Treating Life-threatening Metabolic
Page 22: A 63 year old lady presents with pr
Page 25 and 26: Treatment of Fluid Overload • Avo
Page 27 and 28: Treatment of Acidosis • NaHCO 3 1
Page 29 and 30: Acetate vs. Bicarbonate dialysis Li
Page 31 and 32: Pre - renal A Comparison of Albumin
Page 33 and 34: Bleeding Diathesis • Haematocrit
Page 35 and 36: Prevention of radiocontrast-induced
Page 37 and 38: Fenoldopam Crit Care Med. 2005 Nov;
Page 39 and 40: Atrial Natriuretic Peptide for Mana
Page 41 and 42: Diuretics • Basis : wash away the
Page 43: Growth factors • Basis : After su
Page 47 and 48: Renal Biopsy in ARF • Generally n
Page 49: Acknowledgements • To Prof. Ken F

Pharmacological Management of Acute Kidney Injury

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