Plasmapheresis - CRRT Online
Plasmapheresis - CRRT Online
Plasmapheresis - CRRT Online
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dmward@ucsd.edu<br />
Separation by centrifugation<br />
<strong>Plasmapheresis</strong> (TPE)<br />
(plasma removal or exchange)<br />
High G-force (= high RPM’s) to<br />
create a platelet-poor plasma<br />
Specific Gravity<br />
Plasma 1.027<br />
To get pure cell product:<br />
(1) interface position<br />
(2) accurate RPM’s (G’s)<br />
(3) flow rate (dwell time)<br />
Low G-force to<br />
keep WBC’s out<br />
of packed RBC’s<br />
Thrombocytapheresis<br />
(platelet<br />
removal)<br />
Leukocytapheresis<br />
=<br />
Leukapheresis<br />
(WBC<br />
removal)<br />
Erythrocytapheresis<br />
(red cell<br />
exchange)<br />
Plt’s 1.04<br />
Lymph’s<br />
Mono’s 1.06<br />
Blasts<br />
PMN’s 1.085<br />
RBC’s 1.095
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