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SABM James D. Ferguson, Keith A. Samolyk, Victor Carcioppolo ...

SABM James D. Ferguson, Keith A. Samolyk, Victor Carcioppolo ...

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• Methods – 71 patients were enrolled undergoing isolated CABG<br />

procedures. A Doppler ultrasound was recorded every 8<br />

milliseconds of the inflow and outflow of the CPB circuit. S100B<br />

were measured before surgery and 48 hours after surgery.<br />

• Results – Emboli leaving the CPB circuit was detected in 67<br />

patients. The distribution of microemboli varied across patients.<br />

Most patient had elevated S100B levels following surgery.<br />

• Conclusion – The authors showed an association between<br />

the neurologic injury measured as S100B levels and<br />

microemboli detected in the CPB circuit. They suggest<br />

reductions in neurologic injury may result from redesign<br />

of the CPB circuit to prevent emboli leaving the circuit

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