SABM James D. Ferguson, Keith A. Samolyk, Victor Carcioppolo ...

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Background – Processing of pericardial shed blood with a cell-saving device was claimed to prevent lipid microembolization and to protect from neurocognitive dysfunction after CPB Methods - Forty patients, 65 yrs and older, were prospectively randomized to processing of pericardial shed blood with a cell-saving device or to conventional use of a standard closed venous reservoir where cardiotomy blood was collected and reinfused through the arterial circuit for the control group. Near-infrared Spectroscopy before surgery and at the time of discharge from the hospital. The also looked at protein S100B in all patients. Results – The protein S100B levels averaged 0.06 ± 0.03 before surgery and 0.51 ± 0.23 30 minutes after surgery compared with 0.076 ± 0.04 before surgery and 1.48 ± 0.66 in the control patients. Conclusions – The S100B was significantly higher in the control group vs. the cell saver group. Although the use of the cell-saving device was NOT associated with higher brain oxygen saturation nor changes in the stroke score but it was associated with lesser release of nonspecific markers of brain injury
The Meta-Analysis contained 31 randomized studies and 2282 patients Current evidence suggests that the use of a cell saver reduces exposure to allogenic blood products or red blood cell transfusions for patients undergoing cardiac surgery. Sub- analyses suggest that a cell saver may be beneficial only when it is used for shed blood and/or residual blood or during the entire operative period. Processing cardiotomy suction blood with a cell saver only during CPB has no significant effect on blood conservation and increases fresh frozen plasma transfusion.
Page 1 and 2: SABM James D. Ferguson, Keith A. Sa
Page 3: • It’s time for Perfusion and t
Page 8 and 9: Mortality & Morbidity TRALI (Tx Re
Page 10: • Are there components found in s
Page 16 and 17: • -Proinflammatory mediators •
Page 18: Should we discard cardiotomy suctio
Page 21 and 22: More Cardiotomy Blood Concerns •
Page 23 and 24: “The risk of stroke postoperative
Page 25: • Dr Stump’s s research on card
Page 28 and 29: Approved by the Wake Forest Univers
Page 30: Number of Cerebral Lipid Microembol
Page 33 and 34: • A national survey conducted Jus
Page 35 and 36: • Methods - 71 patients were enro
Page 37: The study showed Shed Mediastinal B
Page 41 and 42: Abstract Objective: During cardiopu
Page 43 and 44: Munir Boodhwani, Howard J. Nathan,
Page 45 and 46: Conclusions from Study Contrary to
Page 47 and 48: So what can we determine from all o
Page 49 and 50: Abstract: Cell salvage devices are
Page 51 and 52: Autotransfusion Pitfalls The potent
Page 53 and 54: Remove 70-90% of soluble contaminan
Page 55 and 56: Quality improves by process change:
Page 57 and 58: We are at a conundrum in cardiac su
Page 59 and 60: 1. Belway, D., Rubens, F., Wonzy, D
Page 61: 13. Shann, K. G., Likosky, D. S., M

SABM James D. Ferguson, Keith A. Samolyk, Victor Carcioppolo ...

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