SABM James D. Ferguson, Keith A. Samolyk, Victor Carcioppolo ...

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• Recent Evidence-Based Guidelines (JTCVS Aug 2006;132(2):283) – “Direct reinfusion to the CPB circuit of unprocessed blood exposed to pericardial and mediastinal surfaces should be avoided (Class I, Level B) – “Blood cell processing and secondary filtration can be considered to decrease the deleterious effects of reinfused shed blood (Class IIb, Level B) • This is the largest randomized, double-blinded study examining the effects of cardiotomy blood processing and can be used to inform the guidelines • Demonstrates the feasibility of double-blinding in trials comparing interventions related to CPB
So what can we determine from all of these studies?? Cell Salvaging is good in a limited amount for lipid removal? Shed blood Contains a plethora of bad stuff and Should this be reinfused? Or not?
Page 1 and 2: SABM James D. Ferguson, Keith A. Sa
Page 3: • It’s time for Perfusion and t
Page 8 and 9: Mortality & Morbidity TRALI (Tx Re
Page 10: • Are there components found in s
Page 16 and 17: • -Proinflammatory mediators •
Page 18: Should we discard cardiotomy suctio
Page 21 and 22: More Cardiotomy Blood Concerns •
Page 23 and 24: “The risk of stroke postoperative
Page 25: • Dr Stump’s s research on card
Page 28 and 29: Approved by the Wake Forest Univers
Page 30: Number of Cerebral Lipid Microembol
Page 33 and 34: • A national survey conducted Jus
Page 35 and 36: • Methods - 71 patients were enro
Page 37 and 38: The study showed Shed Mediastinal B
Page 39 and 40: The Meta-Analysis contained 31 rand
Page 41 and 42: Abstract Objective: During cardiopu
Page 43 and 44: Munir Boodhwani, Howard J. Nathan,
Page 45: Conclusions from Study Contrary to
Page 49 and 50: Abstract: Cell salvage devices are
Page 51 and 52: Autotransfusion Pitfalls The potent
Page 53 and 54: Remove 70-90% of soluble contaminan
Page 55 and 56: Quality improves by process change:
Page 57 and 58: We are at a conundrum in cardiac su
Page 59 and 60: 1. Belway, D., Rubens, F., Wonzy, D
Page 61: 13. Shann, K. G., Likosky, D. S., M

SABM James D. Ferguson, Keith A. Samolyk, Victor Carcioppolo ...

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