SABM James D. Ferguson, Keith A. Samolyk, Victor Carcioppolo ...

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Advantages Disadvantages 1. Higher red cell concentration 2. Higher 2,3 DPG content 3. Reduced osmotic fragility 4. Reduction in foreign debris 5. Reduction in inflammatory mediators 1. Potential for bacterial contamination 2. Platelet damage 3. Loss of plasma and coagulation factors 4. Loss of proteins COP 5. Higher concentration of neutrophils Perfusion 2003; 18: 115-121
Remove 70-90% of soluble contaminants from salvaged blood Fibrin(ogen) Split Products D-Dimers Activated Complement Free Hgb Activate Fibrinolytic Particles Activated WBC – 30%-70% of activated WBC’s are removed with a cell washer (the Fresenius C.A.T.’s system removed the most) Proteolytic Enzymes Anticoagulants Marker Enzymes (CPK) Fats Stroma, Cell Fragments Bacteria and Endotoxins Transfusion 2004;44:35S-39S
Page 1 and 2: SABM James D. Ferguson, Keith A. Sa
Page 3: • It’s time for Perfusion and t
Page 8 and 9: Mortality & Morbidity TRALI (Tx Re
Page 10: • Are there components found in s
Page 16 and 17: • -Proinflammatory mediators •
Page 18: Should we discard cardiotomy suctio
Page 21 and 22: More Cardiotomy Blood Concerns •
Page 23 and 24: “The risk of stroke postoperative
Page 25: • Dr Stump’s s research on card
Page 28 and 29: Approved by the Wake Forest Univers
Page 30: Number of Cerebral Lipid Microembol
Page 33 and 34: • A national survey conducted Jus
Page 35 and 36: • Methods - 71 patients were enro
Page 37 and 38: The study showed Shed Mediastinal B
Page 39 and 40: The Meta-Analysis contained 31 rand
Page 41 and 42: Abstract Objective: During cardiopu
Page 43 and 44: Munir Boodhwani, Howard J. Nathan,
Page 45 and 46: Conclusions from Study Contrary to
Page 47 and 48: So what can we determine from all o
Page 49 and 50: Abstract: Cell salvage devices are
Page 51: Autotransfusion Pitfalls The potent
Page 55 and 56: Quality improves by process change:
Page 57 and 58: We are at a conundrum in cardiac su
Page 59 and 60: 1. Belway, D., Rubens, F., Wonzy, D
Page 61: 13. Shann, K. G., Likosky, D. S., M

SABM James D. Ferguson, Keith A. Samolyk, Victor Carcioppolo ...

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