(ScAg 1501) Final Exam—May 8, 2002 Multiple Choice. Cho

20. Single nucleotide polymrphisms can:
a. Be used as markers associated with a trait
b. Are polymorphisms that are present in a species about every 1000 bp
c. Be used to predict the 3-D conformation of a protein
d. Both a and b
e. Both b and c
21. Dolly the cloned Finn Dorset was the first animal derived
a. Using a Nucleus from an adult cell
b. Using mitochondria
c. Using tissue DNA
d. Using embryonic cells
22. These cells don’t stop growing when they come in contact with each other:
a. Primary
b. Tumor
c. Old
d. Immortal, but not tumorigenic
e. Normal
23. A DNA chip:
a. Represents thousands of expressed sequence tags
b. Can serve as probes for determining expression levels of many different mRNAs
c. Both a and b
d. Is used for the expression analysis of only one gene at a time
24. One of the following answers is NOT true for short tandem repeats:
a. They can identify 1 in 10 18 individuals (when all 13 STRs are analyzed)
b. They are based on highly polymorphic regions of DNA among individuals
c. They have replaced RFLP analysis in most state crime labs
d. They use Southern blot technology
25. The CFTR gene was identified by all of the following methods except:
a. Purification of the mutant protein
b. Chromosome walking
c. Chromosome Mapping
d. DNA sequencing
e. Genetic linkage analyis
26. Treatment for CFTR currently uses gene therapy where the adenovirus:
a. Homes to the lungs
b. Is replication defective
c. Homes to the liver
d. Both a and b