Microbial Diseases of the Nervous System
Microbial Diseases of the Nervous System
Microbial Diseases of the Nervous System
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Fungal Disease <strong>of</strong> <strong>Nervous</strong> <strong>System</strong><br />
Cryptococcus ne<strong>of</strong>ormans Meningitis<br />
• Also called cryptococcosis<br />
• Soil fungus associated with pigeon and chicken<br />
(aerosolization <strong>of</strong> dried up contaminated droppings)<br />
• Transmitted by <strong>the</strong> respiratory route; spreads<br />
through blood to <strong>the</strong> CNS<br />
• Mortality up to 30% – Primarily affects AIDS patients<br />
( .4%)<br />
• Diagnosis: Serology to detect cryptococcal antigens<br />
in serum or CSF<br />
Copyright © 2010 Pearson Education, Inc.
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