FARMACOLOGIA DEL SISTEMA INMUNE
FARMACOLOGIA DEL SISTEMA INMUNE
FARMACOLOGIA DEL SISTEMA INMUNE
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The importance of CD28-mediated costimulation has also been demonstrated in vivo.<br />
Blockade of CD28-mediated costimulation has been shown to:<br />
• Prolong graft survival<br />
• Block primary antibody response<br />
• Prevent or reduce in intensity experimentally, antigen-induced models of<br />
autoimmunity including arthritis, encephalomyelitis, myocarditis, thyroiditis and<br />
myasthenia gravis