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Introduction to Genome Annotation - CPGR

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Experimental Evidence<br />

DNA sequence evidence: Transcript<br />

sequence (EST, full length cDNA, other<br />

expression types); more restrictive in<br />

evolutionary terms<br />

Protein Evidence: alignment <strong>to</strong> protein that<br />

suggests structural similarity at the amino<br />

acid level; can be more distant<br />

evolutionarily

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