Introduction to Genome Annotation - CPGR

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Eukaryotic Gene Structure and Transcript Processing
Structural Annotation: Finding the Genes in Genomic DNA Two main types of data used in defining gene structure: Prediction based: algorithms designed to find genes/gene structures based on nucleotide sequence and composition Sequence similarity (DNA and protein): alignment to mRNA sequences (ESTs) and proteins from the same species or related species; identification of domains and motifs
Page 1 and 2: Introduction to Genome Annotation A
Page 3 and 4: Annotation pipeline Generation of O
Page 5: Prokaryotic Gene Structure and Tran
Page 9 and 10: Candidate Genes 6-frame ORF map Sto
Page 11 and 12: Eukaryotic Gene Finding Identifying
Page 13 and 14: Experimental Evidence DNA sequence
Page 15 and 16: Functional Assignments Name Descrip
Page 17 and 18: Sequence Alignments Compare sequenc
Page 19 and 20: Functional Annotation: Gene Product
Page 21 and 22: Automated Annotation is Not a Solve
Page 23 and 24: Features Typically Resolved During
Page 25: Caveats of Genome Annotation -Great

Introduction to Genome Annotation - CPGR

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