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72 Hyperbaric Oxygenation Therapy KCE Reports 74<br />
Table 25. Distribution functions for input variables<br />
Variable<br />
Base Case<br />
value<br />
Lower<br />
Bound<br />
Upper<br />
Bound<br />
Distribution<br />
Investment 12-multiplace 800 000 750 000 850 000 Uniform<br />
Investment 6-multiplace 710 000 660 000 760 000 Uniform<br />
Investment monoplace 140 000 115 000 165 000 Uniform<br />
Maintenance cost as % of inv. Price 1.5% 1% 2% Beta<br />
For investment price a uniform distribution is applied. For <strong>the</strong> proportion variable<br />
maintenance cost (as % of investment price), a beta distribution is applied. The impact of<br />
lifetime of <strong>the</strong> equipment is afterwards analyzed through one-way sensitivity analysis<br />
(see section 5.9.6).<br />
5.9.5 Results: cost per patient per session<br />
600<br />
500<br />
400<br />
300<br />
200<br />
100<br />
By applying probabilistic modelling and running 1000 Monte Carlo simulations, <strong>the</strong><br />
uncertainty of <strong>the</strong> input variables is translated into uncertainty on <strong>the</strong> result. In <strong>the</strong><br />
following figure (Figure 32), <strong>the</strong> mean cost per patient per session is shown for each of<br />
<strong>the</strong> 36 scenarios. Table 26 also provides <strong>the</strong> credibility interval, total number of patients<br />
being treated and use of personnel.<br />
Figure 32. Average cost per session: 3-way scenario analysis<br />
0<br />
30% 50% 70% 90%<br />
Monoplace - 1 session/day<br />
Monoplace - 2 sessions/day<br />
Monoplace - 3 sessions/day<br />
6-place - 1 session/day<br />
6-place - 2 sessions/day<br />
6-place - 3 sessions/day<br />
12-place - 1 session/day<br />
12-place - 2 sessions/day<br />
12-place - 3 sessions/day