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72 Hyperbaric Oxygenation Therapy KCE Reports 74<br />

Table 25. Distribution functions for input variables<br />

Variable<br />

Base Case<br />

value<br />

Lower<br />

Bound<br />

Upper<br />

Bound<br />

Distribution<br />

Investment 12-multiplace 800 000 750 000 850 000 Uniform<br />

Investment 6-multiplace 710 000 660 000 760 000 Uniform<br />

Investment monoplace 140 000 115 000 165 000 Uniform<br />

Maintenance cost as % of inv. Price 1.5% 1% 2% Beta<br />

For investment price a uniform distribution is applied. For <strong>the</strong> proportion variable<br />

maintenance cost (as % of investment price), a beta distribution is applied. The impact of<br />

lifetime of <strong>the</strong> equipment is afterwards analyzed through one-way sensitivity analysis<br />

(see section 5.9.6).<br />

5.9.5 Results: cost per patient per session<br />

600<br />

500<br />

400<br />

300<br />

200<br />

100<br />

By applying probabilistic modelling and running 1000 Monte Carlo simulations, <strong>the</strong><br />

uncertainty of <strong>the</strong> input variables is translated into uncertainty on <strong>the</strong> result. In <strong>the</strong><br />

following figure (Figure 32), <strong>the</strong> mean cost per patient per session is shown for each of<br />

<strong>the</strong> 36 scenarios. Table 26 also provides <strong>the</strong> credibility interval, total number of patients<br />

being treated and use of personnel.<br />

Figure 32. Average cost per session: 3-way scenario analysis<br />

0<br />

30% 50% 70% 90%<br />

Monoplace - 1 session/day<br />

Monoplace - 2 sessions/day<br />

Monoplace - 3 sessions/day<br />

6-place - 1 session/day<br />

6-place - 2 sessions/day<br />

6-place - 3 sessions/day<br />

12-place - 1 session/day<br />

12-place - 2 sessions/day<br />

12-place - 3 sessions/day

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