Human Health Risk Assessment - Raytheon
Human Health Risk Assessment - Raytheon
Human Health Risk Assessment - Raytheon
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where:<br />
DAD = Dermal absorbed dose (mg/kg-day)<br />
DAevent = Absorbed dose per event (mg/cm 2 -event)<br />
EV = Event frequency (events/day)<br />
EF = Exposure frequency (days/year)<br />
ED = Exposure duration (years)<br />
SA = Exposed skin surface area (cm 2 )<br />
BW = Body weight (kg)<br />
AT = Averaging time (days)<br />
FA = Fraction absorbed water (dimensionless)<br />
Kp = Dermal permeability coefficient (cm/hr)<br />
Cw = Concentration of COPC in Irrigation water (mg/cm 3 )<br />
τ event = Lag time per event (hr/event)<br />
tevent = Event duration (hr/event)<br />
31<br />
<strong>Human</strong> <strong>Health</strong> <strong>Risk</strong> <strong>Assessment</strong><br />
DRAFT<br />
B = Ratio of permeabilities through stratum corneum and viable epidermis<br />
(unitless)<br />
t* = Time to reach steady state (hr)<br />
The LADD is calculated using equation (4-21) with the exception that the ADD is replaced by<br />
the DAD. Exposure point concentrations for on-Site shallow groundwater are reported in Table<br />
5 and exposure factors are summarized in Table 6. Dose and risk calculations for potential<br />
exposures to COPCs via dermal contact with saturated soils and exposed groundwater by on-<br />
Site construction workers are provided in Appendix A; Table A-4.<br />
Incidental Ingestion of Soil. Some incidental ingestion of saturated soil may occur during<br />
subsurface excavation activities. The average daily dose (ADD) from ingestion of soil is<br />
calculated using equation (4-25).<br />
where:<br />
EPC<br />
x IR<br />
x ET x EF x ED<br />
s i<br />
ADD = (4-25)<br />
BW x ATn<br />
EPCs = Exposure point concentration in soil (mg/kg)<br />
IRs = Soil ingestion rate (kg/day)<br />
EF = Exposure frequency (days/year)<br />
ED = Exposure duration (years)<br />
BW = Body weight (kg)