Human Health Risk Assessment - Raytheon

DRAFT
Table 8. Source and Derivation of Toxicity Values
COPCs in Indoor Air
Skin
Absorption
Source
GI Absorption
Source
Cancer Class
Source
IUR 1/(ug/m3)
Source
CSFo
1/(mg/kg-day)
Source
CSFi
1/(mg/kg-day)
Source
CSFd
1/(mg/kg-day)
Carcinogens
benzene 0.9 A A I 7.80E-06 I 5.50E-02 I 2.73E-02 E 6.11E-02 E
chloroethane 1 R NA NA 2.90E-03 N 2.90E-03 E 2.90E-03 E
chloroform 1 A B2 I 2.30E-05 I NA 8.05E-02 E NA
1,2-dichloroethane 1 A B2 H 2.60E-05 I 9.10E-02 I 9.10E-02 E 9.10E-02 E
1,2-dichloropropane 1 A B2 H NA 6.80E-02 H 6.80E-02 E 6.80E-02 E
1,4-dioxane 0.1 9 1 R B2 I NA 1.10E-02 I 1.10E-02 E 1.10E-02 E
methylene chloride 1 A B2 I 4.70E-07 I 7.50E-03 I 1.65E-03 E 7.50E-03 E
tetrachloroethene 1 A NA NA 5.20E-02 N 2.00E-03 N 5.20E-02 E
1,1,2-trichloroethane 0.81 A C I 1.60E-05 I 5.70E-02 I 5.60E-02 E 7.04E-02 E
trichloroethene 0.945 A B2 H NA 1.10E-02 N 6.00E-03 N 1.16E-02 E
vinyl chloride 0.875 A A I 4.40E-06 I 7.20E-01 I 1.54E-02 E 8.23E-01 E
Skin
Absorption
Source
GI Absorption
Source
Critical Effect
Source
RfC
(mg/m3)
Source
RfDo
(mg/kg-day)
Source
RfDi
(mg/kg-day)
Source
RfDd
(mg/kg-day)
NonCarcinogens
acetone 1 R Kidney, Liver, Neuro NA 9.00E-01 I 9.00E-01 E 9.00E-01 E
benzene 0.9 A Blood 3.00E-02 I 4.00E-03 I 8.57E-03 E 3.60E-03 E
carbon disulfide 1 R Development, Neuro 7.00E-01 I 1.00E-01 I 2.00E-01 E 1.00E-01 E
chloroethane 1 R Developmental 1.00E+01 I 4.00E-01 N 2.86E+00 E 4.00E-01 E
chloroform 1 A Liver NA 1.00E-02 I 1.40E-02 N 1.00E-02 E
1,1-dichloroethane 1 R Kidney 5.00E-01 H 1.00E-01 H 1.43E-01 E 1.00E-01 E
1,2-dichloroethane 1 A None Specified NA 3.00E-02 N 3.00E-02 E 3.00E-02 E
1,1-dichloroethene 1 A Liver 2.00E-01 I 5.00E-02 I 5.71E-02 E 5.00E-02 E
cis-1,2-dichloroethene 1 R Blood NA 1.00E-02 H 1.00E-02 E 1.00E-02 E
trans-1,2-dichloroethene 1 R Blood, Liver NA 2.00E-02 I 2.00E-02 E 2.00E-02 E
1,2-dichloropropane 1 A Nasal 4.00E-03 I 1.10E-03 9 1.14E-03 E 1.10E-03 E
1,4-dioxane 0.1 9 1 R NA NA NA NA
ethylbenzene 1 R Develop, Kidney, Liver 1.00E+00 I 1.00E-01 I 2.86E-01 E 1.00E-01 E
isopropylbenzene 1 R Adrenals, Kidney 4.00E-01 I 1.00E-01 I 1.14E-01 E 1.00E-01 E
methyl ethyl ketone 1 R Developmental 5.00E+00 I 6.00E-01 I 1.43E+00 E 6.00E-01 E
methyl isobutyl ketone 1 R Kidney, Liver 3.00E+00 I 8.00E-02 H 8.57E-01 E 8.00E-02 E
methylene chloride 1 A Liver 3.00E+00 H 6.00E-02 I 8.57E-01 E 6.00E-02 E
4-methylphenol 0.745 A Neuro, Respiratory NA 5.00E-03 H 3.73E-03 E 3.73E-03 E
phenol 1 A Developmental NA 3.00E-01 I 3.00E-01 E 3.00E-01 E
tetrachloroethene 1 A Liver NA 1.00E-02 I 1.40E-01 N 1.00E-02 E
toluene 1 R Kidney, Liver, Neuro 5.00E+00 I 8.00E-02 I 1.43E+00 E 8.00E-02 E
1,1,1-trichloroethane 1 HS NA 2.80E-01 N 2.86E-01 N 2.80E-01 E
1,1,2-trichloroethane 0.81 A Liver NA 4.00E-03 I 3.24E-03 E 3.24E-03 E
trichloroethene 0.945 A NA 6.00E-03 N 5.67E-03 E 5.67E-03 E
1,2,4-trimethylbenzene 1 R NA 5.00E-02 N 1.70E-03 N 5.00E-02 E
1,3,5-trimethylbenzene 1 R NA 5.00E-02 N 1.70E-03 N 5.00E-02 E
xylenes 0.895 A Neurological 1.00E-01 I 2.00E-01 I 2.86E-02 E 1.79E-01 E
vinyl chloride 0.875 A Liver 1.00E-01 I 3.00E-03 I 2.86E-02 E 2.63E-03 E
I = IRIS
E = Extrapolated
A = ATSDR
N = NCEA
R = RAGS-E
H = HAL (USEPA's 2002 Edition of the Drinking Water Standards and Health Advisories)
HE = HEAST
HS = HSDB
T = TPHCWG
9 = Region 9 PRG Table
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Human Health Risk Assessment
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