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the egyptian society of cardiology board of ... - Cardioegypt.com

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Ayman Sadek, et al<br />

had documented obstruction <strong>of</strong> distal arteries <strong>of</strong><br />

<strong>the</strong> leg (Peripheral angiography or lower limb<br />

arterial duplex).<br />

The following patients were be excluded from <strong>the</strong><br />

whole study:<br />

Previous neck or femoral irradiation, Previous<br />

neck or femoral surgery, or any neck or lower limb<br />

deformity interfering with carotid or femoral ultrasonography<br />

respectively.<br />

Methods:<br />

Every patient was subjected to <strong>the</strong> following:<br />

Proper history taking and examination:<br />

Full history for <strong>the</strong> presence <strong>of</strong> cardiovascular<br />

risk factors:<br />

Smoking, Hypertension, Diabetes mellitus,<br />

Dyslipidemia, Family history <strong>of</strong> ischemic heart<br />

disease, Symptoms suggestive <strong>of</strong> coronary artery<br />

diseases Peripheral vascular disease Cerebrovascular<br />

strokes or transient ischemic attacks:<br />

Complete general and local clinical examination<br />

with stress on <strong>the</strong> following points:<br />

Weight: Measured in kilograms.<br />

Height: Measured in meters.<br />

Body mass index = Weight in kilograms/(height<br />

in meters) 2<br />

Table 1: Criteria for clinical diagnosis <strong>of</strong> metabolic syndrome.<br />

Measure<br />

(any 3 <strong>of</strong> 5 constitute<br />

diagnosis <strong>of</strong> metabolic<br />

syndrome)<br />

Elevated waist circumference*<br />

Elevated triglycerides<br />

Reduced HDL-C<br />

Elevated blood pressure<br />

Elevated fasting glucose<br />

Categorical<br />

Cutpoints<br />

≥102 cm (≥40 inches) in<br />

men ≥88 cm (≥35 inches)<br />

in women<br />

≥150 mg/dL (1.7<br />

mmol/L)Or On drug<br />

treatment for elevated<br />

triglycerides<br />

≤40 mg/dL (1.03 mmol/L)<br />

in men≤50 mg/dL (1.3<br />

mmol/L) in women<br />

≥130 mm Hg systolic blood<br />

pressure or ≥85 mm Hg<br />

diastolic blood pressure<br />

or On antihypertensive<br />

drug treatment in a patient<br />

with a history <strong>of</strong><br />

hypertension<br />

≥100 mg/dL or On drug<br />

treatment for elevated<br />

glucose<br />

41<br />

Pulse: Radial, brachial with stress on pulse<br />

pressure and dorsalis pedis arteries were examined<br />

for rate, rhythm, volume, special character and<br />

equality <strong>of</strong> pulsations.<br />

Morning urine sample to measure microalbuminuria:<br />

Using HemoCue Urine albumin operator<br />

manuals instrument.<br />

1- We open <strong>the</strong> package and carefully remove <strong>the</strong><br />

cuvette <strong>the</strong>n we fill <strong>the</strong> cuvette by contact with<br />

<strong>the</strong> urine sample (a urine drop on a hydrophilic<br />

surface i.e a plastic film).<br />

2- Open <strong>the</strong> lid and push <strong>the</strong> filled cuvette into <strong>the</strong><br />

cuvette holder.<br />

3- Measuring should begin within 30 seconds after<br />

<strong>the</strong> cuvette has been filled with urine.<br />

4- Within 90 seconds <strong>the</strong> result will be displayed<br />

in mg/dl.<br />

12 lead surface ECG:<br />

Echocardiography:<br />

Echocardiography was done for measurement<br />

<strong>of</strong> (LVEDD), (LVEDD, (EF), (LVPWT) and<br />

(IVST).<br />

And assessment <strong>of</strong> RSWMA.<br />

Carotid and femoral arterial duplex:<br />

All patients underwent ultrasonography <strong>of</strong> <strong>the</strong><br />

right and left carotid and femoral arteries where<br />

<strong>the</strong> following measured:<br />

1- Carotid intima-media thickness (IMT):<br />

The characteristic B-scan pattern <strong>of</strong> <strong>the</strong> arterial<br />

walls shows two parallel echogenic lines separated<br />

by a relatively hypoechoic space "<strong>the</strong> double line<br />

pattern". This pattern is found in <strong>the</strong> posterior wall<br />

<strong>of</strong> <strong>the</strong> <strong>com</strong>mon carotid arteries; <strong>the</strong> inner line is<br />

generally more regular, smooth and thin than <strong>the</strong><br />

outer one and represents <strong>the</strong> lumen intima interface.<br />

The outer one is produced by <strong>the</strong> collagen containing<br />

upper layer <strong>of</strong> tunica adventitia, close to <strong>the</strong><br />

media-adventitia interface.<br />

The intima-media thickness (IMT) is measured<br />

from <strong>the</strong> leading edge <strong>of</strong> <strong>the</strong> inner line to <strong>the</strong><br />

leading edge <strong>of</strong> <strong>the</strong> outer one [14].<br />

An ultrasonographically determined increase<br />

in IMT may be regarded as an indicator <strong>of</strong> generalized<br />

a<strong>the</strong>rosclerosis [15].<br />

We measured <strong>the</strong> carotid IMT bilaterally by Bmode<br />

ultrasonography (7-8MHz linear array, gen-

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