Principles of Chemotherapy - Experimental Oncology Graduate Study
Principles of Chemotherapy - Experimental Oncology Graduate Study
Principles of Chemotherapy - Experimental Oncology Graduate Study
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4. “Platinating” agents: Cisplatin and Carboplatin• Act by a mechanism similar to thealkylating agents.• Cisplatin is used in drug combinationsthat can cure testicular cancer and palliatea variety <strong>of</strong> solid tumors.• Carboplatin is an analogue <strong>of</strong> cisplatinthat has come into clinical use.• Newer compounds include tri-nuclearplatinating agents.25