- Page 1 and 2: TOXICOLOGICAL PROFILE FORCHROMIUMU.
- Page 3: CHROMIUMiiiUPDATE STATEMENTToxicolo
- Page 7 and 8: CHROMIUMviiQUICK REFERENCE FOR HEAL
- Page 11: CHROMIUMxiPEER REVIEWA peer review
- Page 14 and 15: CHROMIUMxiv2.2.3.1 Death ..........
- Page 16: CHROMIUMxviC. ACRONYMS, ABBREVIATIO
- Page 21 and 22: CHROMIUM 11. PUBLIC HEALTH STATEMEN
- Page 23 and 24: CHROMIUM 31. PUBLIC HEALTH STATEMEN
- Page 25 and 26: CHROMIUM 51. PUBLIC HEALTH STATEMEN
- Page 27 and 28: CHROMIUM 71. PUBLIC HEALTH STATEMEN
- Page 29: CHROMIUM 91. PUBLIC HEALTH STATEMEN
- Page 33 and 34: CHROMIUM 132. HEALTH EFFECTS2.1 INT
- Page 35 and 36: CHROMIUM 152. HEALTH EFFECTSconside
- Page 37 and 38: CHROMIUM 172. HEALTH EFFECTSin both
- Page 39 and 40: INTERMEDIATE EXPOSURESystemic7 Huma
- Page 41 and 42: 15 Rabbit 4-6 wk Resp 0.6 M (decrea
- Page 43 and 44: 26 Human27 Human28 Human29 Human0.2
- Page 45 and 46: 36 Rat 2 yr Resp 1.6 (granulomata,
- Page 47 and 48: 51 Mouse 18 rno(C57BL/6) 5 d/wk5 hr
- Page 49 and 50: 0In0sc z14m13m16h15h12r12r12r10r 11
- Page 51 and 52: ~ ~-Figure 2-1. Levels of Significa
- Page 53 and 54: CHROMIUM 332. HEALTH EFFECTSexcessi
- Page 55 and 56: CHROMIUM 352. HEALTH EFFECTShad per
- Page 57 and 58: CHROMIUM 372. HEALTH EFFECTSmedical
- Page 59 and 60: CHROMIUM 392. HEALTH EFFECTSchromat
- Page 61 and 62: CHROMIUM 412. HEALTH EFFECTSGastroi
- Page 63 and 64: CHROMIUM 432. HEALTH EFFECTSengaged
- Page 65 and 66: CHROMIUM 452. HEALTH EFFECTSphospho
- Page 67 and 68: CHROMIUM 472. HEALTH EFFECTSferroch
- Page 69 and 70: CHROMIUM 492. HEALTH EFFECTSBody We
- Page 71 and 72: CHROMIUM 512. HEALTH EFFECTSincreas
- Page 73 and 74: CHROMIUM 532. HEALTH EFFECTSThe occ
- Page 75 and 76: CHROMIUM 552. HEALTH EFFECTSwith co
- Page 77 and 78: CHROMIUM 572. HEALTH EFFECTSinclude
- Page 79 and 80: CHROMIUM 592. HEALTH EFFECTSA cohor
- Page 81 and 82:
CHROMIUM 612. HEALTH EFFECTSreveale
- Page 83 and 84:
CHROMIUM 632. HEALTH EFFECTSchromiu
- Page 85 and 86:
CHROMIUM 652. HEALTH EFFECTSIn a st
- Page 87 and 88:
CHROMIUM 672. HEALTH EFFECTSan asso
- Page 89 and 90:
CHROMIUM 692. HEALTH EFFECTSexamina
- Page 91 and 92:
CHROMIUM 712. HEALTH EFFECTStwo fer
- Page 93 and 94:
CHROMIUM 732. HEALTH EFFECTScaustic
- Page 95 and 96:
TABLE 2-2. Levels of Significant Ex
- Page 97 and 98:
Systemic14 Human15 Human16 Human17
- Page 99 and 100:
INTERMEDIATE EXPOSUREDeath25 Mouse
- Page 101 and 102:
39 Mouse 12wk Bd Wt(Swiss)(W)Bd Wt4
- Page 103 and 104:
52 Rat 9 wk(Sprague- (F)Dawley)53 M
- Page 105 and 106:
66 Mouse Gd12- 74 (reduced ovary an
- Page 107 and 108:
74 Rat 2-3 yr Cardio 0.46(Long- Eva
- Page 109 and 110:
forFigure 2-2. Levels of Significan
- Page 111 and 112:
Figure 2-2. Levels of Significant E
- Page 113 and 114:
CHROMIUM 932. HEALTH EFFECTSvomitin
- Page 115 and 116:
CHROMIUM 952. HEALTH EFFECTSchromiu
- Page 117 and 118:
CHROMIUM 972. HEALTH EFFECTSProtein
- Page 119 and 120:
CHROMIUM 992. HEALTH EFFECTSSplenoc
- Page 121 and 122:
CHROMIUM 1012. HEALTH EFFECTSexamin
- Page 123 and 124:
CHROMIUM 1032. HEALTH EFFECTSsexual
- Page 125 and 126:
CHROMIUM 1052. HEALTH EFFECTSIn the
- Page 127 and 128:
CHROMIUM 1072. HEALTH EFFECTSto pot
- Page 129 and 130:
CHROMIUM 1092. HEALTH EFFECTSSingle
- Page 131 and 132:
Gn pig(NS)Gn pig(NS)Rabbit(NS)Rabbi
- Page 133 and 134:
HumanHumanGn pig(albino)Gn pig(albi
- Page 135 and 136:
CHROMIUM 1152. HEALTH EFFECTSCardio
- Page 137 and 138:
CHROMIUM 1172. HEALTH EFFECTSAcute
- Page 139 and 140:
CHROMIUM 1192. HEALTH EFFECTSchromi
- Page 141 and 142:
CHROMIUM 1212. HEALTH EFFECTSIn a s
- Page 143 and 144:
CHROMIUM 1232. HEALTH EFFECTSdiffus
- Page 145 and 146:
CHROMIUM 1252. HEALTH EFFECTSfor zi
- Page 147 and 148:
CHROMIUM 1272. HEALTH EFFECTSStudie
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CHROMIUM 1292. HEALTH EFFECTSat app
- Page 151 and 152:
CHROMIUM 1312. HEALTH EFFECTSaqueou
- Page 153 and 154:
CHROMIUM 1332. HEALTH EFFECTSChromi
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CHROMIUM 1352. HEALTH EFFECTSsource
- Page 157 and 158:
CHROMIUM 1372. HEALTH EFFECTSTwelve
- Page 159 and 160:
CHROMIUM 1392. HEALTH EFFECTSred bl
- Page 161 and 162:
CHROMIUM 1412. HEALTH EFFECTSinject
- Page 163 and 164:
CHROMIUM 1432. HEALTH EFFECTScorneu
- Page 165 and 166:
CHROMIUM 1452. HEALTH EFFECTSand NA
- Page 167 and 168:
CHROMIUM 1472. HEALTH EFFECTSchromi
- Page 169 and 170:
CHROMIUM 1492. HEALTH EFFECTSresult
- Page 171 and 172:
CHROMIUM 1512. HEALTH EFFECTSRats g
- Page 173 and 174:
CHROMIUM 1532. HEALTH EFFECTSinject
- Page 175 and 176:
CHROMIUM 1552. HEALTH EFFECTSmany b
- Page 177 and 178:
CHROMIUM 1572. HEALTH EFFECTS2.3.5.
- Page 179 and 180:
CHROMIUM 1592. HEALTH EFFECTSTable
- Page 181 and 182:
CHROMIUM 1612. HEALTH EFFECTSincorp
- Page 183 and 184:
CHROMIUM 1632. HEALTH EFFECTSwith t
- Page 185 and 186:
CHROMIUM 1652. HEALTH EFFECTSTissue
- Page 187 and 188:
CHROMIUM 1672. HEALTH EFFECTSThe pr
- Page 189 and 190:
CHROMIUM 1692. HEALTH EFFECTSelevat
- Page 191 and 192:
CHROMIUM 1712. HEALTH EFFECTS1 mg c
- Page 193 and 194:
CHROMIUM 1732. HEALTH EFFECTSThe re
- Page 195 and 196:
CHROMIUM 1752. HEALTH EFFECTSSystem
- Page 197 and 198:
CHROMIUM 1772. HEALTH EFFECTSchromi
- Page 199 and 200:
CHROMIUM 1792. HEALTH EFFECTSleukoc
- Page 201 and 202:
CHROMIUM 1812. HEALTH EFFECTShyperp
- Page 203 and 204:
CHROMIUM 1832. HEALTH EFFECTSNecros
- Page 205 and 206:
CHROMIUM 1852. HEALTH EFFECTSduring
- Page 207 and 208:
CHROMIUM 1872. HEALTH EFFECTSThe th
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CHROMIUM 1892. HEALTH EFFECTSand st
- Page 211 and 212:
CHROMIUM 1912. HEALTH EFFECTSwater
- Page 213 and 214:
CHROMIUM 1932. HEALTH EFFECTSlympho
- Page 215 and 216:
Table 2-5. Genotoxicity of Chromium
- Page 217 and 218:
Species (test system)Subcellular ta
- Page 219 and 220:
Species (test system)Prokaryotic or
- Page 221 and 222:
Species (test system)Mammalian cell
- Page 223 and 224:
Species (test system)Subcellular ta
- Page 225 and 226:
Species (test system)Eukaryotic org
- Page 227 and 228:
CHROMIUM 2072. HEALTH EFFECTSwas fo
- Page 229 and 230:
CHROMIUM 2092. HEALTH EFFECTSIn con
- Page 231 and 232:
CHROMIUM 2112. HEALTH EFFECTSor env
- Page 233 and 234:
CHROMIUM 2132. HEALTH EFFECTSChildr
- Page 235 and 236:
CHROMIUM 2152. HEALTH EFFECTSabnorm
- Page 237 and 238:
CHROMIUM 2172. HEALTH EFFECTScells)
- Page 239 and 240:
CHROMIUM 2192. HEALTH EFFECTSHuman
- Page 241 and 242:
CHROMIUM 2212. HEALTH EFFECTSFigure
- Page 243 and 244:
CHROMIUM 2232. HEALTH EFFECTShad no
- Page 245 and 246:
CHROMIUM 2252. HEALTH EFFECTS5 fema
- Page 247 and 248:
CHROMIUM 2272. HEALTH EFFECTS0.1 µ
- Page 249 and 250:
CHROMIUM 2292. HEALTH EFFECTSRecent
- Page 251 and 252:
CHROMIUM 2312. HEALTH EFFECTS2.11 M
- Page 253 and 254:
CHROMIUM 2332. HEALTH EFFECTSpotass
- Page 255 and 256:
CHROMIUM 2352. HEALTH EFFECTSN,N,N'
- Page 257 and 258:
CHROMIUM 2372. HEALTH EFFECTSDiffer
- Page 259 and 260:
CHROMIUM 2392. HEALTH EFFECTS
- Page 261 and 262:
CHROMIUM 2412. HEALTH EFFECTSA majo
- Page 263 and 264:
CHROMIUM 2432. HEALTH EFFECTSlethal
- Page 265 and 266:
CHROMIUM 2452. HEALTH EFFECTSanimal
- Page 267 and 268:
CHROMIUM 2472. HEALTH EFFECTSchroma
- Page 269 and 270:
CHROMIUM 2492. HEALTH EFFECTSresult
- Page 271 and 272:
CHROMIUM 2512. HEALTH EFFECTSeffect
- Page 273 and 274:
CHROMIUM 2532. HEALTH EFFECTSgenoto
- Page 275 and 276:
CHROMIUM 2552. HEALTH EFFECTSadditi
- Page 277 and 278:
CHROMIUM 2572. HEALTH EFFECTS2.12.3
- Page 279 and 280:
CHROMIUM 2593. CHEMICAL AND PHYSICA
- Page 281 and 282:
CharacteristicSynonym(s)Table 3-1.
- Page 283 and 284:
CharacteristicTable 3-1. Chemical I
- Page 285 and 286:
CharacteristicTable 3-1. Chemical I
- Page 287 and 288:
CHROMIUM 2673. CHEMICAL AND PHYSICA
- Page 289 and 290:
CHROMIUM 2693. CHEMICAL AND PHYSICA
- Page 291 and 292:
CHROMIUM 2713. CHEMICAL AND PHYSICA
- Page 293 and 294:
CHROMIUM 2734. PRODUCTION, IMPORT/E
- Page 295 and 296:
CHROMIUM 2754. PRODUCTION, IMPORT/E
- Page 297 and 298:
CHROMIUM 2774. PRODUCTION, IMPORT/E
- Page 299:
CHROMIUM 2794. PRODUCTION, IMPORT/E
- Page 302 and 303:
Derived from HazDat 2000Figure 5-1.
- Page 304 and 305:
CHROMIUM 2845. POTENTIAL FOR HUMAN
- Page 306 and 307:
CHROMIUM 2865. POTENTIAL FOR HUMAN
- Page 308 and 309:
State bTable 5-2. Releases to the E
- Page 310 and 311:
CHROMIUM 2905. POTENTIAL FOR HUMAN
- Page 312 and 313:
CHROMIUM 2925. POTENTIAL FOR HUMAN
- Page 314 and 315:
CHROMIUM 2945. POTENTIAL FOR HUMAN
- Page 316 and 317:
CHROMIUM 2965. POTENTIAL FOR HUMAN
- Page 318 and 319:
CHROMIUM 2985. POTENTIAL FOR HUMAN
- Page 320 and 321:
CHROMIUM 3005. POTENTIAL FOR HUMAN
- Page 322 and 323:
CHROMIUM 3025. POTENTIAL FOR HUMAN
- Page 324 and 325:
CHROMIUM 3045. POTENTIAL FOR HUMAN
- Page 326 and 327:
CHROMIUM 3065. POTENTIAL FOR HUMAN
- Page 328 and 329:
CHROMIUM 3085. POTENTIAL FOR HUMAN
- Page 330 and 331:
CHROMIUM 3105. POTENTIAL FOR HUMAN
- Page 332 and 333:
CHROMIUM 3125. POTENTIAL FOR HUMAN
- Page 334 and 335:
CHROMIUM 3145. POTENTIAL FOR HUMAN
- Page 336 and 337:
Sample matrixTable 6-1. Analytical
- Page 338 and 339:
CHROMIUM 3186. ANALYTICAL METHODSth
- Page 340 and 341:
Sample matrixAir (totalchromium)Air
- Page 342 and 343:
Sample matrixAtomosphericdeposition
- Page 344 and 345:
Sample matrixSoil, sedimentand slud
- Page 346 and 347:
CHROMIUM 3266. ANALYTICAL METHODSpr
- Page 348 and 349:
CHROMIUM 3287. REGULATIONS AND ADVI
- Page 350 and 351:
CHROMIUM 3307. REGULATIONS AND ADVI
- Page 352 and 353:
CHROMIUM 3327. REGULATIONS AND ADVI
- Page 354 and 355:
CHROMIUM 3347. REGULATIONS AND ADVI
- Page 356 and 357:
CHROMIUM 3367. REGULATIONS AND ADVI
- Page 358 and 359:
CHROMIUM 3387. REGULATIONS AND ADVI
- Page 360 and 361:
CHROMIUM 3408. REFERENCES*Albert RE
- Page 362 and 363:
CHROMIUM 3428. REFERENCES*ATSDR. 19
- Page 364 and 365:
CHROMIUM 3448. REFERENCESBerg NO, B
- Page 366 and 367:
CHROMIUM 3468. REFERENCES*Bragt PC,
- Page 368 and 369:
CHROMIUM 3488. REFERENCESCarter WW.
- Page 370 and 371:
CHROMIUM 3508. REFERENCESCohen MD,
- Page 372 and 373:
CHROMIUM 3528. REFERENCES*De Flora
- Page 374 and 375:
CHROMIUM 3548. REFERENCES*Elbetieha
- Page 376 and 377:
CHROMIUM 3568. REFERENCES*EPA. 1987
- Page 378 and 379:
CHROMIUM 3588. REFERENCES*Fagliano
- Page 380 and 381:
CHROMIUM 3608. REFERENCESFregert S,
- Page 382 and 383:
CHROMIUM 3628. REFERENCES*Glaser U,
- Page 384 and 385:
CHROMIUM 3648. REFERENCES*Hallmark
- Page 386 and 387:
CHROMIUM 3668. REFERENCESHneihen AS
- Page 388 and 389:
CHROMIUM 3688. REFERENCESIkarashi Y
- Page 390 and 391:
CHROMIUM 3708. REFERENCESKamath SM,
- Page 392 and 393:
CHROMIUM 3728. REFERENCES*Kirkpatri
- Page 394 and 395:
CHROMIUM 3748. REFERENCES*Krishnan
- Page 396 and 397:
CHROMIUM 3768. REFERENCESLarsen EH,
- Page 398 and 399:
CHROMIUM 3788. REFERENCES*Liden S,
- Page 400 and 401:
CHROMIUM 3808. REFERENCESLucia-Jand
- Page 402 and 403:
CHROMIUM 3828. REFERENCESMathur AK,
- Page 404 and 405:
CHROMIUM 3848. REFERENCESMiksche LW
- Page 406 and 407:
CHROMIUM 3868. REFERENCESMyers MJ,
- Page 408 and 409:
CHROMIUM 3888. REFERENCES*NIOSH. 19
- Page 410 and 411:
CHROMIUM 3908. REFERENCES*Offenbach
- Page 412 and 413:
CHROMIUM 3928. REFERENCES*Paustenba
- Page 414 and 415:
CHROMIUM 3948. REFERENCESRafnsson V
- Page 416 and 417:
CHROMIUM 3968. REFERENCESRyberg D,
- Page 418 and 419:
CHROMIUM 3988. REFERENCES*Schuhmach
- Page 420 and 421:
CHROMIUM 4008. REFERENCES*Simpson J
- Page 422 and 423:
CHROMIUM 4028. REFERENCESSteenland
- Page 424 and 425:
CHROMIUM 4048. REFERENCESSunderman
- Page 426 and 427:
CHROMIUM 4068. REFERENCES*Triebig G
- Page 428 and 429:
CHROMIUM 4088. REFERENCES*Venier P,
- Page 430 and 431:
CHROMIUM 4108. REFERENCES*Wedeen RP
- Page 432 and 433:
CHROMIUM 4128. REFERENCESWong PK. 1
- Page 435 and 436:
CHROMIUM 4159. GLOSSARYAbsorption
- Page 437 and 438:
CHROMIUM 4179. GLOSSARYImmediately
- Page 439 and 440:
CHROMIUM 4199. GLOSSARYand physiolo
- Page 441:
CHROMIUM 4219. GLOSSARYToxicokineti
- Page 444 and 445:
CHROMIUM A-2APPENDIX AMRLs are inte
- Page 446 and 447:
CHROMIUM A-4APPENDIX AUncertainty f
- Page 448 and 449:
CHROMIUM A-6APPENDIX Aincreased in
- Page 451 and 452:
CHROMIUM B-1APPENDIX BUSER'S GUIDEC
- Page 453 and 454:
CHROMIUM B-3APPENDIX Beffects. The
- Page 455 and 456:
13141516(ppm)1000010001001010.10.01
- Page 457:
CHROMIUM B-7APPENDIX BTo derive an
- Page 460 and 461:
CHROMIUM C-2APPENDIX CLC LoLC 50LD