TOXICOLOGICAL PROFILE FOR CHROMIUM - Davidborowski.com

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forFigure 2-1. Levels of Significant Exposure to Chromium - InhalationAcute (114 days)Systemic0Ix05CK1000100101rVIVI3r2rVI4rVI5rVIh,Irn5Irnnrn0-i(n1Q6s1116sIII0.1c-Cat -Humans f-Ferret n-Mink Cancer Effect Level-Animals Cancer Effect Level-Humans LD50/LC50d-Dog k-Monkey j-Pigeon o-Other LOAEL, More Serious-Animals LOAEL, More Serious-Humans I Minimal Riskr-Rat m-Mouse e-Gerbil 8 LOAEL, Less Serious-Animals LOAEL, Less Serious-Humans ~ effectsp-Pig h-Rabbit s-Hamster 0 NOAEL -Animals A NOAEL - Humansother Cancer thanq-Cow a-Sheep g-Guinea Pig
0In0sc z14m13m16h15h12r12r12r10r 11r 10r 11r 10r 11r 10r 11r 10r11r12r17r18r21r7 811r12r10r912r11r12r19r20rPrnF-IIrn-nnrn04v,Cancer Effect Level-Animals Cancer Effect Level-Humans LD50/LC50d-Dog k-Monkey j-Pi eon o-Other 0 LOAEL, More Serious-Animals A LOAEL, More Serious-Humans I Minimal Riskr-Rat m-Mouse e-&rbil @ LOAEL, Less Serious-Animals A LOAEL, Less Serious-Humans I for effectsp-Pig h-Rabbit s-Hamster 0 NOAEL -Animals NOAEL - Humans A other thann-Cnw a-Sheen n-Giiinea Pin Cancer
Page 1 and 2: TOXICOLOGICAL PROFILE FORCHROMIUMU.
Page 3: CHROMIUMiiiUPDATE STATEMENTToxicolo
Page 7 and 8: CHROMIUMviiQUICK REFERENCE FOR HEAL
Page 11: CHROMIUMxiPEER REVIEWA peer review
Page 14 and 15: CHROMIUMxiv2.2.3.1 Death ..........
Page 16: CHROMIUMxviC. ACRONYMS, ABBREVIATIO
Page 21 and 22: CHROMIUM 11. PUBLIC HEALTH STATEMEN
Page 29: CHROMIUM 91. PUBLIC HEALTH STATEMEN
Page 32 and 33: CHROMIUM 121. PUBLIC HEALTH STATEME
Page 34 and 35: CHROMIUM 142. HEALTH EFFECTSessenti
Page 36 and 37: CHROMIUM 162. HEALTH EFFECTSuncerta
Page 38 and 39: TABLE 2-1. Levels of Significant Ex
Page 40 and 41: 11 Rat 90 d Resp 0.025 M (increased
Page 42 and 43: 20 Rat(Wistar)Reproductive90 d7 d/w
Page 44 and 45: 33 Rat I8 mo Resp 0.1 M Glaser et a
Page 46 and 47: 43 Human44 Human45 Human46 Human47
Page 50 and 51: 35r 35r 35r 35r 35r 35r 35r 35r 35r
Page 52 and 53: CHROMIUM 322. HEALTH EFFECTSInterme
Page 54 and 55: CHROMIUM 342. HEALTH EFFECTSexposur
Page 56 and 57: CHROMIUM 362. HEALTH EFFECTSsulfate
Page 58 and 59: CHROMIUM 382. HEALTH EFFECTScorrela
Page 60 and 61: CHROMIUM 402. HEALTH EFFECTS1953).
Page 62 and 63: CHROMIUM 422. HEALTH EFFECTSBaltimo
Page 64 and 65: CHROMIUM 442. HEALTH EFFECTSHepatic
Page 66 and 67: CHROMIUM 462. HEALTH EFFECTSdichrom
Page 68 and 69: CHROMIUM 482. HEALTH EFFECTSdamage
Page 70 and 71: CHROMIUM 502. HEALTH EFFECTSChromiu
Page 72 and 73: CHROMIUM 522. HEALTH EFFECTSAn exte
Page 74 and 75: CHROMIUM 542. HEALTH EFFECTS2.2.1.7
Page 76 and 77: CHROMIUM 562. HEALTH EFFECTS2.2.1.8
Page 78 and 79: CHROMIUM 582. HEALTH EFFECTSmajor p
Page 80 and 81: CHROMIUM 602. HEALTH EFFECTSfound a
Page 82 and 83: CHROMIUM 622. HEALTH EFFECTSsignifi
Page 84 and 85: CHROMIUM 642. HEALTH EFFECTSheavy s
Page 86 and 87: CHROMIUM 662. HEALTH EFFECTScarcino
Page 88 and 89: CHROMIUM 682. HEALTH EFFECTS(female
Page 90 and 91: CHROMIUM 702. HEALTH EFFECTSFerroch
Page 92 and 93: CHROMIUM 722. HEALTH EFFECTS1.2x10
Page 94 and 95: CHROMIUM 742. HEALTH EFFECTSchromiu
Page 96 and 97: 8 Rat once 26 M (LD 50)(Fischer- 34
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20 Mouse 9 d Bd Wt 53.2 F 101 .1 F
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32 Rat(BD)33 RatSwiss albino34 RatD
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Neurological45 Rat 28 d(Wistar)Repr
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59 Mouse 85 d + 36.7 F NTP 1997(BAL
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CHRONIC EXPOSURESystemic70 Human71
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Figure 2-2. Levels of Significant E
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MinimalFigure 2-2. Levels of Signif
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CHROMIUM 922. HEALTH EFFECTSand blo
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CHROMIUM 942. HEALTH EFFECTSHematol
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CHROMIUM 962. HEALTH EFFECTSAverage
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CHROMIUM 982. HEALTH EFFECTSchanges
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CHROMIUM 1002. HEALTH EFFECTSsperma
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CHROMIUM 1022. HEALTH EFFECTSchromi
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CHROMIUM 1042. HEALTH EFFECTS2.2.2.
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CHROMIUM 1062. HEALTH EFFECTSImpair
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CHROMIUM 1082. HEALTH EFFECTSrates
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TABLE 2-3. Levels of Significant Ex
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HumanHumanHumanHumanHumanHumanHuman
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CHRONIC EXPOSURESystemicHuman 7.5 y
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CHROMIUM 1162. HEALTH EFFECTSNo stu
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CHROMIUM 1182. HEALTH EFFECTSIrrita
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CHROMIUM 1202. HEALTH EFFECTSindust
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CHROMIUM 1222. HEALTH EFFECTSGuinea
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CHROMIUM 1242. HEALTH EFFECTSmodel,
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CHROMIUM 1262. HEALTH EFFECTSblood,
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CHROMIUM 1302. HEALTH EFFECTSAlthou
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CHROMIUM 1322. HEALTH EFFECTS2.3.2
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CHROMIUM 1362. HEALTH EFFECTSThe di
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CHROMIUM 1382. HEALTH EFFECTS(2-5 m
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CHROMIUM 1402. HEALTH EFFECTSIn rat
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CHROMIUM 1422. HEALTH EFFECTSunstab
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CHROMIUM 1442. HEALTH EFFECTSIn add
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CHROMIUM 1462. HEALTH EFFECTSsignif
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CHROMIUM 1502. HEALTH EFFECTSDaily
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CHROMIUM 1522. HEALTH EFFECTS51 Chr
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CHROMIUM 1562. HEALTH EFFECTSFigure
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CHROMIUM 1582. HEALTH EFFECTSTable
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CHROMIUM 1622. HEALTH EFFECTSInterr
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CHROMIUM 1642. HEALTH EFFECTSthe bl
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CHROMIUM 1662. HEALTH EFFECTSpreval
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CHROMIUM 1682. HEALTH EFFECTS2.5 RE
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CHROMIUM 1702. HEALTH EFFECTSSevera
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CHROMIUM 1722. HEALTH EFFECTSanimal
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CHROMIUM 1742. HEALTH EFFECTSOral M
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CHROMIUM 1762. HEALTH EFFECTSfibros
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CHROMIUM 1782. HEALTH EFFECTSNausea
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CHROMIUM 1802. HEALTH EFFECTSthe pr
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CHROMIUM 1822. HEALTH EFFECTSSevere
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CHROMIUM 1842. HEALTH EFFECTSdevelo
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CHROMIUM 1862. HEALTH EFFECTSthe ce
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CHROMIUM 1882. HEALTH EFFECTSimprov
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CHROMIUM 1902. HEALTH EFFECTSchroma
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CHROMIUM 1922. HEALTH EFFECTSIn ano
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Table 2-5. Genotoxicity of Chromium
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Table 2-5. Genotoxicity of Chromium
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Species (test system)Prokaryotic or
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Species (test system)S. typhimurium
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Species (test system)Mouse A18BcR c
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Species (test system)Prokaryotic or
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Species (test system)Syrian hamster
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CHROMIUM 2082. HEALTH EFFECTSet al.
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CHROMIUM 2102. HEALTH EFFECTScancer
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CHROMIUM 2122. HEALTH EFFECTS2.6 EN
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CHROMIUM 2142. HEALTH EFFECTSChromi
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CHROMIUM 2182. HEALTH EFFECTSBiolog
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CHROMIUM 2222. HEALTH EFFECTSemploy
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CHROMIUM 2242. HEALTH EFFECTSunexpe
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CHROMIUM 2262. HEALTH EFFECTSMutti
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CHROMIUM 2282. HEALTH EFFECTS1986a,
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CHROMIUM 2302. HEALTH EFFECTSconcen
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CHROMIUM 2322. HEALTH EFFECTSmentio
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CHROMIUM 2362. HEALTH EFFECTSglutat
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CHROMIUM 2382. HEALTH EFFECTS1997).
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CHROMIUM 2402. HEALTH EFFECTS
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CHROMIUM 2422. HEALTH EFFECTSlimite
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CHROMIUM 2442. HEALTH EFFECTSThe re
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CHROMIUM 2462. HEALTH EFFECTS(Nette
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CHROMIUM 2482. HEALTH EFFECTSsperma
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CHROMIUM 2502. HEALTH EFFECTSThere
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CHROMIUM 2522. HEALTH EFFECTStimesp
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CHROMIUM 2542. HEALTH EFFECTSShmito
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CHROMIUM 2562. HEALTH EFFECTShas no
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CHROMIUM 2582. HEALTH EFFECTSTable
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CharacteristicSynonym(s)Table 3-1.
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CHROMIUM 2663. CHEMICAL AND PHYSICA
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CHROMIUM 2744. PRODUCTION, IMPORT/E
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CHROMIUM 2815. POTENTIAL FOR HUMAN
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Derived from HazDat 2000Figure 5-2.
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State bTable 5-2. Releases to the E
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State bTable 5-2. Releases to the E
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CHROMIUM 3156. ANALYTICAL METHODSTh
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Sample matrixTable 6-1. Analytical
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CHROMIUM 3196. ANALYTICAL METHODS6.
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Sample matrixOccupational air(weldi
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Sample matrixWaste water 1986(chrom
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CHROMIUM 3256. ANALYTICAL METHODS6.
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CHROMIUM 3277. REGULATIONS AND ADVI
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CHROMIUM 3398. REFERENCES*Aaseth J,
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CHROMIUM 3418. REFERENCES*Anderson
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CHROMIUM 3438. REFERENCES*Baranowsk
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CHROMIUM 3458. REFERENCESBlack CB,
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CHROMIUM 3478. REFERENCES*Buckell M
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CHROMIUM 3498. REFERENCES*Chen NSC,
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CHROMIUM 3518. REFERENCESCriqui M,
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CHROMIUM 3538. REFERENCESDOD. 1947.
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CHROMIUM 3558. REFERENCES*EPA. 1984
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CHROMIUM 3578. REFERENCES*EPA. 1996
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CHROMIUM 3598. REFERENCESFlint GN,
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CHROMIUM 3618. REFERENCES*Gale TF,
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CHROMIUM 3638. REFERENCESGriepink B
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CHROMIUM 3658. REFERENCES*Hayes RB,
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CHROMIUM 3678. REFERENCESHunt CD, S
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CHROMIUM 3698. REFERENCES*Jansen LH
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CHROMIUM 3718. REFERENCESKeith RL,
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CHROMIUM 3738. REFERENCES*Korallus
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CHROMIUM 3758. REFERENCES*Laborda R
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CHROMIUM 3778. REFERENCESLees PSJ,
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CHROMIUM 3798. REFERENCES*Liu KJ, J
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CHROMIUM 3818. REFERENCES*Malm O, P
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CHROMIUM 3838. REFERENCESMehra R, B
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CHROMIUM 3858. REFERENCES*Morris B,
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CHROMIUM 3878. REFERENCES*Newbold R
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CHROMIUM 3898. REFERENCES*Novey HS,
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CHROMIUM 3918. REFERENCES*OSHA 1999
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CHROMIUM 3938. REFERENCESPiela Z, K
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CHROMIUM 3958. REFERENCESRI Div Air
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CHROMIUM 3978. REFERENCES*Sata F, A
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CHROMIUM 3998. REFERENCES*Sheppard
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CHROMIUM 4018. REFERENCES*Snyder CA
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CHROMIUM 4038. REFERENCESŠtupar J,
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CHROMIUM 4058. REFERENCESTamino G,
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CHROMIUM 4078. REFERENCES*Ueno S, S
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CHROMIUM 4098. REFERENCESWahlberg J
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CHROMIUM 4118. REFERENCES*Wiegand H
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CHROMIUM 4138. REFERENCES*Zhitkovic
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CHROMIUM 4169. GLOSSARYCase Series
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CHROMIUM 4189. GLOSSARYModifying Fa
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CHROMIUM 4209. GLOSSARYeither under
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CHROMIUM A-1APPENDIX AATSDR MINIMAL
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CHROMIUM A-3APPENDIX AMINIMAL RISK
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CHROMIUM A-5APPENDIX AMINIMAL RISK
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CHROMIUM A-7APPENDIX AWas a convers
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CHROMIUM B-2APPENDIX B(2) Exposure
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1SAMPLE6 TABLE 2-1. Levels of Signi
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CHROMIUM B-6APPENDIX BChapter 2 (Se
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CHROMIUM C-1APPENDIX CACRONYMS, ABB
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CHROMIUM C-3APPENDIX CTRITWAU.S.UFy
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TOXICOLOGICAL PROFILE FOR CHROMIUM - Davidborowski.com

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