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SLED - CRRT Online

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<strong>SLED</strong> in VA/NIH ATN Trial• Stratification to RRT modality by cSOFA score:– Score >2 allocated to <strong>CRRT</strong>/<strong>SLED</strong> (55%)– Score ≤2 allocated to IHD (45%)• <strong>CRRT</strong> represented >95% of treatments– Supported by additional observational studies/trials• <strong>CRRT</strong> is the “Standard of care” for hemodynamicallyunstable patients• Clinicians do not yet believe <strong>SLED</strong>/EDD is equivalent to<strong>CRRT</strong> (or have little experience)ATN Trial NEJM 2008; Ronco et al Crit Care 2008; Uchino et al IJAO 2007; Bell et al ICM 2007

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