BME 4900 Final Report - Biomedical Engineering - University of ...

Table of Contents1 Introduction ............................................................................................................................ 11.1 Background .................................................................................................................................... 11.2 Project Purpose ............................................................................................................................ 21.3 Previous Work Done by Others .............................................................................................. 21.3.1 Products ................................................................................................................................................... 41.3.2 Patents ...................................................................................................................................................... 41.4 Report Outline............................................................................................................................... 42 Project Design ........................................................................................................................ 52.1 Background .................................................................................................................................... 52.2 Optimal Design ............................................................................................................................. 92.2.1 Objective .................................................................................................................................................. 92.2.2 Generalized Neuron Circuit .......................................................................................................... 112.2.3 Superior Colliculus ........................................................................................................................... 192.2.4 Cerebellum ........................................................................................................................................... 202.2.5 Excitatory Burst Neuron ................................................................................................................ 212.2.6 Long-Lead Burst Neuron ................................................................................................................ 212.2.7 Tonic Neuron ...................................................................................................................................... 212.2.8 Omnipause Neuron .......................................................................................................................... 222.2.9 Inhibitory Burst Neuron ................................................................................................................ 222.2.10 Abducens Nucleus .......................................................................................................................... 222.2.11 Oculomotor Nucleus ...................................................................................................................... 232.2.12 Circuitry Case ................................................................................................................................... 232.2.13 Observation of Signals .................................................................................................................. 243 Realistic Constraints ......................................................................................................... 254 Safety Issues ......................................................................................................................... 275 Impact of Engineering Solutions ................................................................................... 286 Life-Long Learning ............................................................................................................. 297 Budget & Timeline ............................................................................................................. 317 .1 Budget .......................................................................................................................................... 317.2 Timeline ....................................................................................................................................... 328 Team Member Contributions ......................................................................................... 358.1 Justin Morse ................................................................................................................................ 358.2 Dean Poulos ................................................................................................................................ 358.3 Edward Ryan ............................................................................................................................... 369 Conclusion ............................................................................................................................ 36